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Latest Growth factor Stories

2011-04-25 14:25:24

Scientists close in on molecular moves that let tumor cells act as stowaways in lymphatic system Cancer has a mighty big bag of tricks that it uses to evade the body's natural defense mechanisms and proliferate. Among those tricks is one that allows tumor cells to turn the intricate and extensive system of lymphatic vessels into something of a highway to metastasis. Yet research unveiled this week may aid in the development of therapeutics that will put the brakes on such cancer spread, and...

2011-02-07 14:58:48

A low cost, nanometer-sized drug to treat chronic wounds, such as diabetic foot ulcers or burns, has been developed by a group of scientists from the Hebrew University of Jerusalem, Harvard Medical School and others in the U.S. and Japan. Diabetes is a rapidly growing medical problem affecting close to 3 percent of the world's population. Poor blood circulation arising from diabetes often results in skin wounds which do not heal, causing pain, infection and at times amputation of limbs....

2010-10-26 13:57:00

PALO ALTO, Calif., Oct. 26 /PRNewswire/ -- Telik, Inc. (Nasdaq: TELK) announced today that Telintra (Ezatiostat HCl), the company's lead therapeutic product candidate, has been selected by Windhover Information and its advisors as one of "The Top 10 Most Interesting Oncology Projects to Watch." Windhover is a leading provider of business information to senior executives in the pharmaceutical, biotechnology, and medical device industries. The company has been invited to present at...

2010-09-21 09:41:00

TORONTO, Sept. 21 /PRNewswire/ -- According to Millennium Research Group (MRG), the global authority on medical technology market intelligence, the introduction and adoption of new growth factors, combined with greater variety and improved features of newer products, will drive the US bone graft substitute market to nearly $2.3 billion through 2015. Medtronic Spinal & Biologics' new bone morphogenetic protein, AMPLIFY, is set to be released in the US market in 2011. Unlike INFUSE,...

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2010-08-16 12:31:35

A new study describes how a carbohydrate-binding protein, galectin-3, promotes angiogenesis, the growth of new blood vessels. Targeting the protein, scientists identified two approaches that significantly reduced angiogenesis in mice. These discoveries, published online August 16 in The Journal of Experimental Medicine, may lead to novel treatments for diseases caused by excessive angiogenesis, including age-related macular degeneration, cancer, and diabetes. When the body needs to expand its...

2010-08-12 15:39:33

Blood vessel permeabilty Dr. Jean-Philippe Gratton, Director of the Endothelial cell biology research unit at the Institut de recherches cliniques de Montr©al (IRCM), identifies a new intracellular mechanism responsible for modulating vascular permeability: the nitrosylation of beta-catenin protein by nitric oxide. This scientific breakthrough could have a possible impact on the treatment of cancerous tumours by altering the permeability of the blood vessels irrigating them. Dr....

2010-07-21 15:52:46

American Heart Association meeting report Implanting tiny plastic scaffolds seeded with genetically engineered stem cells reduced organ damage and led to better cardiac function after a heart attack, according to an animal study presented at the American Heart Association's Basic Cardiovascular Sciences 2010 Scientific Sessions "“ Technological and Conceptual Advances in Cardiovascular Disease. The study was designed to help determine what role cytokines "“ substances secreted by...

2010-04-20 14:22:50

By examining tissue removed during breast reduction surgery in healthy women, researchers at Georgetown Lombardi Comprehensive Center have found a molecule they say identified women who had atypical hyperplasia, a potentially precancerous condition in which cells are abnormally increased. Their findings, presented at the AACR 101st Annual Meeting 2010, suggest that this protein, transforming growth factor beta 1 (TGF-ÃŽ²1), could be part of a panel of genes and proteins that...

2010-04-05 07:05:15

MicroRNA-mediated blood vessel development may have potential Most solid cancers can't grow beyond a limited size without an adequate blood supply and supporting vascular network. Because of this, cancer researchers have sought to understand how a tumor's vascular network develops"”and, more importantly, how to prevent it from developing: If the vascular network never develops, the theory goes, the tumor cannot grow. Researchers at the University of Massachusetts Medical School have...

2010-03-18 12:58:43

Findings reveal why a longstanding treatment works, and suggest better approaches Hemangiomas -- strawberry-like birthmarks that commonly develop in early infancy -- are generally harmless, but up to 10 percent cause tissue distortion or destruction and sometimes obstruction of vision or breathing. Since the 1960s, problematic hemangiomas have been treated with corticosteroids such as dexamethasone or prednisone. But steroids have considerable side effects, don't always work, and their...