Quantcast

Latest Growth factor Stories

2010-04-05 07:05:15

MicroRNA-mediated blood vessel development may have potential Most solid cancers can't grow beyond a limited size without an adequate blood supply and supporting vascular network. Because of this, cancer researchers have sought to understand how a tumor's vascular network develops"”and, more importantly, how to prevent it from developing: If the vascular network never develops, the theory goes, the tumor cannot grow. Researchers at the University of Massachusetts Medical School have...

2010-03-18 12:58:43

Findings reveal why a longstanding treatment works, and suggest better approaches Hemangiomas -- strawberry-like birthmarks that commonly develop in early infancy -- are generally harmless, but up to 10 percent cause tissue distortion or destruction and sometimes obstruction of vision or breathing. Since the 1960s, problematic hemangiomas have been treated with corticosteroids such as dexamethasone or prednisone. But steroids have considerable side effects, don't always work, and their...

2010-01-20 14:26:24

Scientists trying to understand how cancer cells invade healthy tissue have used the fruit fly's metamorphosis from maggot to flying insect as a guide to identify a key molecular signal that may be involved in both processes. The research by a team at the University of Rochester Medical Center, published as the cover article in the January issue of the journal Developmental Cell, identifies a molecule that is key for determining how cells invade and create new tissues. That process, which is...

c36ecab30e0eeb2f545b7c4a4464b3bd1
2010-01-19 11:49:25

Researchers at the University of Helsinki, Finland, and the Paul Scherrer Institute (PSI) in Villigen, Switzerland, have determined the crystal structure of the ligand binding domain of a vascular endothelial growth factor (VEGF) receptor in complex with one of its ligands (VEGF-C). Cancer cells require access to blood and lymph vessels for invasive growth and metastasis. By releasing VEGFs, cancer cells stimulate the surrounding blood vessels to invade the cancerous tumor mass. Blocking this...

2009-12-28 13:28:50

Researchers from the University of Hong Kong and the Massachusetts Institute of Technology have published a study in the current issue of Cell Transplantation (18:9), now freely available on line at http://www.ingentaconnect.com/content/cog/ct, that explores ways to successfully keep stem cells "forever young" during implantation by slowing their growth, differentiation and proliferation. "The successful storage and implantation of stem cells poses significant challenges for tissue...

2009-10-06 08:04:52

Results: MIT engineers have boosted stem cells' ability to regenerate vascular tissue (such as blood vessels) by equipping them with genes that produce extra growth factors (naturally occurring compounds that stimulate tissue growth). In a study in mice, the researchers found that the stem cells successfully generated blood vessels near the site of an injury, allowing damaged tissue to survive. Why it matters: Stem cells hold great potential as a way to promote tissue regeneration. However,...

2009-09-21 07:07:45

A common biological molecule is central to placental growth and could hold the key to mitigating growth restriction of babies in the womb Scientists funded by the Biotechnology and Biological Sciences Research Council (BBSRC) have shown that a common biological protein molecule called SHP-2 is crucial for encouraging placenta growth. The research is published yesterday in Endocrinology. Dr Melissa Westwood, one of the team at the University of Manchester said: "For fetuses to grow well in the...

2009-08-28 10:05:43

Scientists in the Academy of Finland's Neuroscience Research Programme have reported promising new results with potential implications for the treatment of Parkinson's disease. They have been studying the impacts of nerve growth factors in the treatment of PD, and their latest results show that a certain growth factor can be used to halt the progress of damage brought on by a nerve poison and possibly even restore the function of damaged cells.The studies on nerve growth factors used an...

2009-08-24 16:06:23

Researchers at INSERM (France) have engineered a chimeric protein that increases cell survival, migration and proliferation to improve stem cell engraftment. The results, which appear in the September 2009 issue of Experimental Biology and Medicine, show that TAT-Tpr-Met, a cell permeable form of the hepatocyte growth factor receptor can increase the number of hepatic stem cells integrated into the liver of the mouse. TAT-Tpr-Met is the result of the fusion of Tpr-Met, an autoactived tyrosine...

2009-07-30 08:00:00

SAN DIEGO, July 30 /PRNewswire-FirstCall/ -- Cardium Therapeutics (NYSE Amex: CXM) today announced plans to develop a DNA-based orthobiologics product portfolio based on research and development by Cardium's Tissue Repair Company that will initially focus on non-union bone fractures for medically-compromised patients, and spinal fusion for patients with degenerative disc disease. Orthobiologics is a rapidly growing segment of the orthopedics market and represents biologically-active...


Word of the Day
lunula
  • A small crescent-shaped structure or marking, especially the white area at the base of a fingernail that resembles a half-moon.
This word is a diminutive of the Latin 'luna,' moon.
Related