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Latest Growth factor Stories

2009-07-30 06:26:11

A drug used to remove iron from the body could help doctors fight one of diabetes' cruelest complications -- poor wound healing -- which can lead to infection and amputation. The drug deferoxamine helped diabetic mice heal small cuts 10 days faster than those who did not receive treatment, according to researchers from Stanford University School of Medicine and the Albert Einstein College of Medicine. The team is now working to arrange human trials for deferoxamine. If the results translate,...

2009-07-24 11:35:00

Scientists at Burnham Institute for Medical Research (Burnham) have found that the Caspase-8 protein, long known to play a major role in promoting programmed cell death (apoptosis), helps relay signals that can cause cancer cells to proliferate, migrate and invade surrounding tissues. The study was published in the journal Cancer Research on June 15.The team of scientists, led by Kristiina Vuori, M.D., Ph.D., professor and director of the Cancer Center at Burnham, showed that Caspase-8 caused...

2009-07-23 08:51:19

Dr. Yasuni Nakanuma and colleagues of Kanazawa University Graduate School of Medicine in Kanazawa, Japan have discovered that BMP-7 (bone morphogenic protein-7) is a potential new therapy for treating high blood pressure in the liver. These results are presented in the August 2009 issue of The American Journal of Pathology.Idiopathic portal hypertension (IPH) is a form of high blood pressure that often results from blockage of the peripheral veins in the liver. Cells that line blood vessels...

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2009-07-15 09:30:00

The research team led by Dr. Timm Schroeder, stem cell researcher at Helmholtz Zentrum Mnchen, has developed a new bioimaging method for observing the differentiation of hematopoietic progenitor cells (HPC) at the single-cell level. With this method the researchers were able to prove for the first time that not only cell-intrinsic mechanisms, but also external environmental factors such as growth factors can control HPC lineage choice directly. The findings, published in the current issue of...

2009-07-15 07:48:59

For decades scientists from various disciplines have discussed to what respective extent genetic predisposition and environmental factors influence human development. Likewise, the same "Ëœnature vs. nurture' issue is debated by hematologists and stem cell researchers: Is multipotent progenitor cell differentiation influenced solely by cell-intrinsic mechanisms or is it also influenced by the environment of the cell? What role do growth factors such as cytokines play? Do they...

2009-06-09 13:44:30

 To grow and spread, tumors need new blood vessels, a process called angiogenesis. One growth factor that causes angiogenesis has been identified -  vascular endothelial growth factor or  VEGF - and drugs to inhibit VEGF are already in use. But not all tumors respond to the therapy initially or over the long term. Thus new growth factors need to be identified to aid in developing the next generation of angiogenesis inhibitors.Scientists at the UNC Lineberger Comprehensive...

2009-05-28 08:00:00

SAN DIEGO, May 28 /PRNewswire-FirstCall/ -- Cardium Therapeutics (NYSE Amex: CXM) and its subsidiary Tissue Repair Company (TRC) today announced a presentation entitled "Phase 2b Study of GAM501 (Ad5PDGF-B/Collagen) in the Treatment of Diabetic Ulcers" at the Late Stage Industry Clinical Trials Symposium at the American Society of Gene Therapy (ASGT) Annual meeting in San Diego, California, on May 27, 2009. Dr. Barbara K. Sosnowski, Cardium's Vice President of Biologics Development and the...

2009-05-20 14:13:20

Research in mice and human stem cells suggests new therapeutic targets Most cancers are rare in people with Down syndrome, whose overall cancer mortality is below 10 percent of that in the general population. Since they have an extra copy of chromosome 21, it's been proposed that people with Down syndrome may be getting an extra dose of one or more cancer-protective genes. The late cancer researcher Judah Folkman, MD, founder of the Vascular Biology Program at Children's Hospital Boston,...

2009-04-07 13:32:00

BOSTON, April 7 /PRNewswire-USNewswire/ -- Scientists at Schepens Eye Research Institute have found that the growth factor known as TGF-beta is essential to the health of blood vessels in the retina and that blocking it can cause retinal dysfunction. These findings, published in the April 2 issue of PLoS ONE, may have an important impact on the prevention and treatment of diseases such as diabetic retinopathy and macular degeneration. "These results are significant because they add to our...

2009-04-07 09:07:47

U.S. medical scientists say they have discovered the first evidence of cell-to-cell communication that uses amino acids. Researchers from the Massachusetts General Hospital's Center for Engineering in Medicine said they were startled to find amino acids were used for cellular interactions rather than known protein signaling agents such as growth factors or cytokines. We were taken by complete surprise, said study lead author Rohit Jindal. Past reports have implicated various growth factors...


Word of the Day
lunula
  • A small crescent-shaped structure or marking, especially the white area at the base of a fingernail that resembles a half-moon.
This word is a diminutive of the Latin 'luna,' moon.
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