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Latest GSK716155 Stories

2012-08-09 23:19:36

Manipulating a group of hormone-producing cells in the brain can control blood sugar levels in the body — a discovery that has dramatic potential for research into weight-loss drugs and diabetes treatment. In a paper published in the October issue of Genetics and available online now, neurobiologists at Wake Forest University examine how fruit flies (Drosophila) react when confronted with a decreased diet. Reduced diet or starvation normally leads to hyperactivity in fruit flies...

2012-04-13 05:28:42

(Ivanhoe Newswire) -- Maintaining the right level of sugar in the blood is the responsibility not only of insulin, which removes glucose, but also of a hormone called glucagon, which adds glucose. For decades, treatments for type II diabetes have taken aim at insulin, but a new study suggests that a better approach may be to target glucagon's sweetening effect. "What we've found is a way to reduce glucagon's influence on blood sugar without the side effects of global glucagon...

2012-04-12 21:04:31

Maintaining the right level of sugar in the blood is the responsibility not only of insulin, which removes glucose, but also of a hormone called glucagon, which adds glucose. For decades, treatments for type II diabetes have taken aim at insulin, but a new study suggests that a better approach may be to target glucagon's sweetening effect. "What we've found is a way to reduce glucagon's influence on blood sugar without the side effects of global glucagon repression," said Ira Tabas, MD,...

2012-01-11 11:22:56

Giving overweight or obese patients a gut hormone that suppresses appetite leads to clinically beneficial weight loss as well as reduced blood pressure and cholesterol levels, finds a study published on bmj.com today. Glucagon-like peptide-1 (GLP-1) is a hormone that is secreted from the intestine when we eat. GLP-1 based therapy was recently introduced as a new treatment for patients with type 2 diabetes because of its ability to regulate blood sugar levels. But it also suppresses food...

2011-11-07 16:53:42

Type 1 diabetes is a lifelong disease characterized by high levels of sugar (glucose) in the blood. It is caused by the patient's immune system attacking and destroying the cells in their pancreas that produce the hormone insulin, which regulates blood glucose levels. Surprisingly, little is known about the mechanisms regulating the sensitivity and resistance of these cells, which are known as beta-cells, to immune system attack. However, a team of researchers led by Paola Meda, at the...

2010-02-17 07:00:00

INDIANAPOLIS, Feb. 17 /PRNewswire/ -- Marcadia Biotech Inc. today announced that it has initiated a Phase 1 clinical trial of MAR701, a novel dual agonist of the incretin hormone receptors for glucagon-like peptide-1 (GLP-1) and gastric inhibitory peptide (GIP). Marcadia plans to initially develop this compound as a treatment for type 2 diabetes with once-weekly dosing. The Phase 1 trial will evaluate MAR701 in healthy volunteers at escalating dose levels. MAR701 targets two peptide...


Word of the Day
omadhaun
  • A fool; a simpleton: a term of abuse common in Ireland and to a less extent in the Gaelic-speaking parts of Scotland.
This word is partly Irish in origin.