Latest GSTM4 Stories

2012-07-02 10:24:09

Ewing´s sarcoma is a bone cancer commonly diagnosed in about 250 U.S. teenagers per year. If early chemotherapy is effective, improvement can be durable. But for children and teens who respond poorly to a first attempt at chemotherapy or if the disease spreads, long-term survival can be less than 10 percent. A University of Colorado Cancer Center study published this week in the journal Molecular Cancer Research shows an important difference that may explain why some respond and some...

2009-08-31 08:52:30

U.S. scientists studying Ewing's sarcoma -- a type of bone cancer -- have found high levels of a specific protein can suppress chemotherapy effects. Researchers at the University of Utah's Huntsman Cancer Institute discovered some patients with Ewing's sarcoma -- which typically afflicts children and young adults -- have poor outcomes if their tumors have high levels of a protein known as GSTM4. Our research shows that GSTM4 is found in high levels among those patients where chemotherapy...

2009-08-31 09:37:59

 Researchers at Huntsman Cancer Institute (HCI) at the University of Utah have shed new light on Ewing's sarcoma, an often deadly bone cancer that typically afflicts children and young adults. Their research shows that patients with poor outcomes have tumors with high levels of a protein known as GSTM4, which may suppress the effects of chemotherapy. The research is published online today in the journal Oncogene."Doctors and researchers have long known that certain Ewing's sarcoma...

Word of the Day
  • A goblin in English folklore, often appearing in the shape of a large dog and believed to portend imminent death or misfortune.
  • A ghost, wraith, hobgoblin, elf, or spirit.
The origin of 'barghest' is not known, but it may be from perhaps burh-ghest, town-ghost, or German Berg-geist (mountain spirit) or Bär-geist (bear-spirit).