Latest Guanidines Stories

H2 Blocker drugs, such as Famotidine, Cimetidine and Ranitidine, approved in the U.S. for acid reflux (heartburn), pose no significant risks for the fetus according to a large collaborative cohort study by researchers at Ben-Gurion University of the Negev.The study published in the Journal of Clinical Pharmacology provides significant reassurance for the safety of the fetus when H2 blocker drugs are given to women to relieve acid reflux during pregnancy.H2 blockers are among the most...

LOURES, Portugal, September 8 /PRNewswire/ -- Hovione is pleased to announce that its TwinCaps(R) inhaler licensees Daiichi Sankyo Co. Ltd. (Tokyo, Japan) and Biota Holdings Ltd (Victoria, Australia) have both announced successful Phase III trials for CS-8958, a new long-acting neuraminidase inhibitor for treatment of influenza (known as a prodrug of laninamivir). CS-8958, co-owned by Daiichi Sankyo and Biota, is delivered by TwinCaps(R), a patented dry powder inhaler which Hovione...

Taking the most commonly-prescribed anti-diabetic drug, metformin, reduces the risk of developing pancreatic cancer by 62 percent, according to research from The University of Texas M. D. Anderson Cancer Center."This is the first epidemiological study of metformin in the cancer population, and it offers an exciting direction for future chemoprevention research for a disease greatly in need of both treatment and prevention strategies," Donghui Li, Ph.D., lead author and professor in...

LAS VEGAS, July 13 /PRNewswire-FirstCall/ -- GNC, the leading global specialty retailer of nutritional products, announced today clinical results for the first and only nitric oxide product, Amplified Maxertion N.O., proven to demonstrate a delay in the onset of neuromuscular fatigue. The key findings were unveiled at the National Strength and Conditioning Association (NSCA) conference in Las Vegas, NV. GNC's Amplified Maxertion N.O.(TM) was shown to increase power output at the onset of...

With the H1N1 flu outbreak now elevated to pandemic level, a new article http://www.cmaj.ca/cgi/rapidpdf/cmaj.090866 in CMAJ (Canadian Medical Association Journal) reports that oseltamivir (Tamiflu®) and zanamivir (Relenza®) are relatively safe drugs for use in pregnant and breast-feeding women.Pregnant women, especially those in the third trimester, are at high risk of serious complications from the H1N1 A influenza virus.The study was conducted by researchers from the Motherisk...

Taking the diabetes medications metformin and rosiglitazone together reverses the adverse effects on bone of rosiglitazone treatment alone in an experimental model, according to a new study done in rats. The results were presented at The Endocrine Society's 91st Annual Meeting in Washington, D.C.Both metformin and rosiglitazone are widely used in the treatment of type 2 diabetes and the metabolic syndrome, said lead author Claudia Sedlinsky, MD, of GIOMM - La Plata National University, La...

- Company preparing to initiate phase III trial - SOUTH SAN FRANCISCO, Calif., March 30 /PRNewswire/ -- Hyperion Therapeutics, Inc. today announced top-line results from their phase II study of HPN-100 for the treatment of urea cycle disorders. The data was presented on March 27th at the 16th Annual Clinical Genetics Meeting of the American College of Medical Genetics by Brendan Lee, M.D., Ph.D., Howard Hughes Medical Institute Investigator and Professor Department of Molecular and Human...

An amino acid found in watermelon juice, nuts and other foods may fight obesity, U.S. researchers say. The study, published in the Journal of Nutrition, finds rats fed either low-fat or high-fat diets supplemented with the amino acid arginine over a 12-week period decreased body fat by over 60 percent. This finding could be directly translated into fighting human obesity. At this time, arginine has not been incorporated into our food but could in the future, study leader Guoyao Wu of Texas...

A Texas AgriLife Research scientist and fellow researchers have discovered that arginine, an amino acid, reduces fat mass in diet-induced obese rats and could help fight human obesity."Given the current epidemic of obesity in the U.S. and worldwide, our finding is very important," said Dr. Guoyao Wu, an AgriLife Research animal nutritionist in College Station and Senior Faculty Fellow in the department of animal science at Texas A&M University.The research found dietary arginine...

Swedish researchers have found that an enzyme that aids sexual performance in human males helps spruce trees develop stronger root systems. A team led by Torgny Nasholm, a forestry professor at the Swedish University of the Agricultural Sciences, created a fertilizer laced with arginine, Vasterbotten-Kurrien reported. The enzyme improves sperm production and blood circulation in the genital area. Nasholm found that trees given the fertilizer had stronger root systems. As an additional...