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Latest Haematopoiesis Stories

Protein Critical To Hematopoietic Stem Cell Function And Blood Formation Identified
2014-02-03 08:09:16

University of California - San Diego Researchers at the University of California, San Diego School of Medicine have identified a protein critical to hematopoietic stem cell function and blood formation. The finding has potential as a new target for treating leukemia because cancer stem cells rely upon the same protein to regulate and sustain their growth. Hematopoietic stem cells give rise to all other blood cells. Writing in the February 2, 2014 advance online issue of Nature Genetics,...

2013-10-21 13:27:21

Scientists report in Nature they have found a novel and unexpected molecular switch that could become a key to slowing some of the ravages of getting older as it prompts blood stem cells to age. The study is expected to help in the search for therapeutic strategies to slow or reverse the aging process, and possibly rejuvenate these critically important stem cells (called hematopoietic stem cells, or HSCs), said scientists from Cincinnati Children's Hospital Medical Center and the...

2013-07-22 08:29:06

Frank Pascale to lead Commercialization of FDA 510K Cleared SynGenX(TM)-1000 Cord Blood Processing Systems SACRAMENTO, Calif., July 22, 2013 /PRNewswire/ -- SynGen Inc., a company focused on the clinical implementation of medical systems that harvest stem and progenitor cells, from cord blood, bone marrow, peripheral blood, and other tissues, announced today that it has appointed Frank Pascale, formerly Senior Vice President of Business Development for Pall Medical, to lead its Cord...

Biologists Show RNA Molecule Protects Stem Cells During Inflammation
2013-05-22 09:37:34

California Institute of Technology When infections occur in the body, stem cells in the blood often jump into action by multiplying and differentiating into mature immune cells that can fight off illness. But repeated infections and inflammation can deplete these cell populations, potentially leading to the development of serious blood conditions such as cancer. Now, a team of researchers led by biologists at the California Institute of Technology (Caltech) has found that, in mouse models,...

2013-03-22 09:59:04

Research shows fewer donor cells may be needed for transplantation and bone marrow banking may be possible More than 50,000 stem cell transplants are performed each year worldwide. A research team led by Weill Cornell Medical College investigators may have solved a major issue of expanding adult hematopoietic stem cells (HSCs) outside the human body for clinical use in bone marrow transplantation -- a critical step towards producing a large supply of blood stem cells needed to restore a...

2013-01-23 10:36:14

Researchers at Imperial College London have shown that keeping healthy blood cells alive could be a more important tool in the fight against leukemia than keeping cancerous cells at bay. The team used computer modelling to show that maintaining a friendly environment for healthy cells was more effective than targeting the damaged cells directly. This result could change the way leukemia is treated, as cancer treatment has traditionally relied on fighting disease rather than maintaining...

2012-01-26 02:12:48

Scientists with the new Children´s Research Institute at UT Southwestern Medical Center have identified the environment in which blood-forming stem cells survive and thrive within the body, an important step toward increasing the safety and effectiveness of bone-marrow transplantation. Institute investigators led by Dr. Sean Morrison asked which cells are responsible for the microenvironment that nurtures haematopoietic stem cells, which produce billions of new blood cells every day....

Penn Study Unlocks Origins of Blood Stem Cells
2011-12-11 06:00:06

A research team led by Nancy Speck, PhD, professor of Cell and Developmental Biology at the Perelman School of Medicine at the University of Pennsylvania, has discovered a molecular marker for the immediate precursors of hematopoietic (blood) stem cells (HSCs) in the developing embryo, which provides much-needed insights for making these cells from engineered precursors. Because HSCs, found in the bone marrow of adult mammals, generate all of the blood cell types of the body, unlocking the...

Scientists Successfully Expand Bone Marrow-derived Stem Cells In Culture
2011-09-16 06:54:07

  All stem cells–regardless of their source–share the remarkable capability to replenish themselves by undergoing self-renewal. Yet, so far, efforts to grow and expand scarce hematopoietic (or blood-forming) stem cells in culture for therapeutic applications have been met with limited success. Now, researchers at the Stowers Institute for Medical Research teased apart the molecular mechanisms enabling stem cell renewal in hematopoietic stem cells isolated from mice and...

2011-07-15 14:47:32

Researches near goal of using a patient's own cells to make stem cells that can replace lost or diseased tissue Scientists at the Salk Institute for Biological Studies have developed an improved technique for generating large numbers of blood cells from a patient's own cells. The new technique will be immediately useful in further stem cell studies, and when perfected, could be used in stem cell therapies for a wide variety of conditions including cancers and immune ailments. "There are...


Latest Haematopoiesis Reference Libraries

Thymus
2013-03-04 12:56:08

The thymus gland is an endocrine organ of the immune system located anteriolateral to the trachea and in between the lungs. Its primary function is to build T lymphocytes for the body’s immune system; therefore, it is most important during childhood and puberty, when it reaches its maximum size. After puberty, it will begin to atrophy and shrink in size. Old age generally brings about hypotrophy of the thymus. In children the thymus is grayish-pink in color and in adults it is yellow. On...

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