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Latest Haematopoiesis Stories

2009-04-09 15:39:05

U.S.-led scientists say they have identified a gene that can protect against leukemia and other blood cancers, possibly paving the way for new therapies. The University of California-San Francisco researchers said they discovered the JunB gene controls the rapid production and differentiation of stem cells that produce all blood cell types. Additionally, the scientists said they uncovered evidence that could lead to a protocol for bone marrow transplants that could boost the chance of a cure...

2009-04-01 08:25:58

For the first time, scientists have shown that amniotic fluid (the protective liquid surrounding an embryo) may be a potential new source of stem cells for therapeutic applications. The study was prepublished online on February 12, 2009, in Blood, the official journal of the American Society of Hematology. "Building on observations made by other scientists, our research team wondered whether stem cells could be detected in amniotic fluid. We looked at the capacity of these cells to form new...

2009-02-11 11:27:28

Using a mouse model of human leukemia, researchers have unlocked more information about the genetic factors related to the generation and maintenance of leukemia stem cells. The discovery is likely to have profound impact on how future therapy can be designed to target cancer stem cells. Leukemia stem cells (LSCs) were initially described as rare cells that share characteristics with normal hematopoietic stem cells (HSCs). HSCs are known as partially committed adult stem cells that can give...

2009-02-06 08:32:53

Stem cells of any kind are defined by their eternal nature, reproducing themselves and providing a pool of cells from which more differentiated tissues arise.Now a group of researchers from Baylor College of Medicine in collaboration with researchers in Australia and the United Kingdom, demonstrate that two specific "sister" genes that control transcription play often overlapping roles in maintaining this pool of hematopoietic or blood cell-forming stem cells.Redundant rolesIn a report in the...

2009-01-05 08:22:59

A type of stem cell responsible for all blood and immune system cells reproduces much more slowly than expected. Using this subpopulation of hematopoietic stem cells may help treatment of leukemia and other marrow-based diseases by improving the outcome of stem cell transplants, also referred to as bone marrow transplants. The entire population of hematopoietic stem cells (HSCs) in bone marrow are believed to reproduce at a rate of about 7 percent per day, with each cell dividing every two...

2008-12-16 09:53:12

 Using stem cell lines not typically combined, researchers at Columbia University Medical Center have designed a new way to "grow" bone and other tissues.The inability to foster angiogenesis "“ a physiological process involving the growth of new blood vessels from pre-existing vessels "“ has been a major roadblock in tissue regeneration. Previous approaches have included the use of angiogenic growth factors and the fabrication of artificial blood vessels. However, there are...

2008-12-05 16:19:57

Investigators from Massachusetts General Hospital (MGH) have found a subpopulation of hematopoietic stem cells, the source of all blood and immune system cells, that reproduce much more slowly than previously anticipated. Use of these cells may improve the outcome of stem cell transplants "“ also called bone marrow transplants "“ for the treatment of leukemia and other marrow-based diseases. The report will appear in the journal Nature Biotechnology and is being released online to...

2008-12-04 10:57:16

Stem cells derived from bone marrow may serve as a novel therapeutic option to treat a disease called epidermolysis bullosa (EB), a disorder characterized by extraordinarily fragile skin, according to a study prepublished online in Blood, the official journal of the American Society of Hematology.Epidermolysis bullosa is a disorder characterized by extraordinarily fragile skin and blistering on touch, akin to third degree burns. While the disease is often lethal in the neonatal period, more...

2006-01-31 00:45:00

By Maggie Fox, Health and Science Correspondent WASHINGTON (Reuters) - Scientists have found blood stem cells hiding out in the edges of bone marrow, and said on Monday their finding could help ease lifesaving stem cell transplants for diseases such as cancer. They invented a technique that makes it possible to see a stem cell alive in bone marrow -- something never done before. Scientists usually find the powerful but elusive cells by looking for proteins called markers that are active on...

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2006-01-24 08:10:10

Discovery could aid bone marrow transplants, gene therapy, researchers say Scientists have discovered a "cocktail" of growth factors that expands the number of stem cells they can grow in the laboratory at least 10 times beyond what anyone has been able to do before. The technique, if replicated in humans, could greatly enhance the effectiveness of bone marrow transplants, and may even help refine gene therapy, the researchers said. Their findings appear in the Jan. 22 online issue of Nature...


Latest Haematopoiesis Reference Libraries

Thymus
2013-03-04 12:56:08

The thymus gland is an endocrine organ of the immune system located anteriolateral to the trachea and in between the lungs. Its primary function is to build T lymphocytes for the body’s immune system; therefore, it is most important during childhood and puberty, when it reaches its maximum size. After puberty, it will begin to atrophy and shrink in size. Old age generally brings about hypotrophy of the thymus. In children the thymus is grayish-pink in color and in adults it is yellow. On...

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Word of the Day
grass-comber
  • A landsman who is making his first voyage at sea; a novice who enters naval service from rural life.
According to the OED, a grass-comber is also 'a sailor's term for one who has been a farm-labourer.'