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Last updated on April 17, 2014 at 21:23 EDT

Latest HARS Stories

2012-11-08 08:34:58

SAN DIEGO and WASHINGTON, Nov. 8, 2012 /PRNewswire/ -- aTyr Pharma, an innovator in immune-modulating protein therapeutics, announced today their presentation at the 2012 American College of Rheumatology (ACR) / Association of Rheumatology Health Professionals (ARHP) Annual Meeting, which is being held November 9-14 in Washington, D.C. The presentation provides an in-depth molecular characterization of Jo-1 antibodies, which occur as part of a rare, human autoimmune response to histidyl tRNA...

2009-12-14 12:45:46

The work provides insight into potential therapeutic for cancer and eye diseases Researchers at The Scripps Research Institute have solved a 10-year-old mystery of how a single protein from an ancient family of enzymes can have two completely distinct roles in the body. In addition to providing guidance for understanding other molecules in the family, the research supplies a theoretical underpinning for the protein's possible use for combating diseases including cancer and macular...

2009-12-14 05:00:00

SAN DIEGO, Dec. 14 /PRNewswire/ -- Research published in the December 13, 2009 edition of Nature Structural Biology uncovers the structural basis for the multifunctionality of aminoacyl tRNA synthetases. Aminoacyl tRNA synthetases are universal and essential enzymes of protein synthesis machinery found in all organisms. However, human synthetases and naturally occurring variants of these enzymes have additional activities that are vital to normal functioning of the complex human system...

2009-07-13 05:00:00

SAN DIEGO, July 13 /PRNewswire/ -- Research published in the June 26, 2009 edition of Proceedings of National Academy of Sciences provides further evidence for novel roles of tRNA synthetases in disease, validating the therapeutic potential for aTyr Pharma's new class of naturally occurring protein agents. The aminoacyl tRNA synthetases are universal and essential components of protein synthesis machinery found in all organisms, but human synthetases have naturally occurring resected...

2009-06-24 12:55:03

 A team of scientists from The Scripps Research Institute, Katholeike Universiteit Leuven, and the University of Antwerp, Belgium, among other institutions, has created a genetically modified fruit fly that mimics key features of Charcot-Marie-Tooth disease, a common neurodegenerative disorder that strikes about one out of every 2,500 people in the United States.As described in an article published in an Early Edition of the journal Proceedings of the National Academy of Sciences the...