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Latest Hedgehog signaling pathway Stories

2014-06-25 08:32:36

$1.5 million in proceeds to fund 2014 commencement of HPPI's clinical development program for repurposing the approved anti-fungal drug itraconazole for the treatment of cancer, initially for the treatment of Basal Cell Carcinoma Nevus Syndrome TAMPA, Fla. and SAN DIEGO, June 25, 2014 /PRNewswire/ -- HedgePath Pharmaceuticals, Inc. (OTCQB:HPPI) a clinical stage biopharmaceutical company that discovers, develops and plans to commercialize innovative therapeutics for patients with...

2014-06-17 08:28:27

Company to Present at BIO International Convention 2014 LOS ANGELES, June 17, 2014 /PRNewswire/ -- MAX BioPharma (www.maxbiopharma.com)announced today that it has successfully designed and synthesized proprietary small molecule oxysterols that are bone-targeted and possess potent osteogenic activity. The research was conducted as part of MAX BioPharma's first SBIR grant-supported activities in the area of osteoporosis. The company believes that these novel molecules are ideal...

2014-06-01 08:20:47

The study met the primary endpoint with objective response rates of 41.8% and 32.5% respectively in the 200 mg and 800 mg treatment arms(1,2) EAST HANOVER, N.J., June 1, 2014 /PRNewswire/ -- Novartis announced today the results of a pivotal Phase II trial demonstrating that patients with locally advanced (laBCC) or metastatic basal cell carcinoma (mBCC) taking the investigational oral compound LDE225 (sonidegib) had marked and sustained tumor shrinkage after a median follow-up of...

2014-05-27 11:56:22

University of Massachusetts at Amherst A new study of how biodiversity arises shows how a mutation in a single gene during development can lead to different consequences not only in jaw shape, but how this leads to different feeding strategies to exploit different ecological niches A new study of how biodiversity arises, by evolutionary biologists at the University of Massachusetts Amherst, shows how a mutation in a single gene during development can lead to different consequences not...

Single Cell Type Found To Cause Most Invasive Bladder Cancers: Study
2014-04-21 09:27:49

Lawrence LeBlond for redOrbit.com - Your Universe Online Invasive bladder cancer (IBC), a malignant disease that currently affects more than 375,000 people worldwide, has been found to be caused by a single type of cell in the lining of the bladder, according to researchers with the Stanford University School of Medicine. The researchers say this is the first study to pinpoint the normal cell type that can give rise to IBC. It is also the first study to show that most bladder cancers...

2014-01-08 12:28:08

Presentation to be held at Monday, January 13, 2014 at 10:00 a.m. Pacific Time at the Parc 55 Wyndam in Union Square, San Francisco TAMPA, Fla. and SAN DIEGO, Jan. 8, 2014 /PRNewswire/ -- HedgePath Pharmaceuticals, Inc. (OTCQB: HPPI), a clinical stage biopharmaceutical company that discovers, develops and plans to commercialize innovative therapeutics for patients with cancer, announced today that its president and chief executive officer, Mr. Nicholas J. Virca, will present at the...

Mouse Study Offers Hope For Potential Down Syndrome Treatment
2013-09-05 06:07:35

April Flowers for redOrbit.com - Your Universe Online A new compound that dramatically bolsters learning and memory when given on the day of birth to mice with a Down syndrome-like condition has been identified by researchers from Johns Hopkins and the National Institutes of Health (NIH). The findings, published in Science Translational Medicine, shows that the single-dose treatment seems to enable the cerebellum of the rodent’s brains to grow to a normal size. The compound is a small...

2012-06-19 22:07:38

Combining a new targeted therapy with standard chemotherapy may help defeat pancreatic cancer, according to results presented at the American Association for Cancer Research's Pancreatic Cancer: Progress and Challenges conference, held here June 18-21. "We believe that GDC-0449 has the potential to change the approach to treating pancreatic cancer," said Edward J. Kim, M.D., Ph.D., a medical oncologist at the University of Michigan Comprehensive Cancer Center in Ann Arbor, Mich....

2012-04-03 09:09:25

Johns Hopkins investigators are testing a way to use drugs that target a cholesterol pathway to enhance the cancer-killing potential of standard chemotherapy drugs. Their tests, in mouse models of pancreatic cancer, may yield new and more effective combinations of current and possibly new anti-cancer drugs. Besides their deadly consequences, pancreatic cancer and heart disease share a connection with genetic pathways that control cholesterol and a cell signaling system known as the...

2012-04-02 21:07:54

Brown University biologists have found a new molecule in fruit flies that is key to the information exchange needed to build wings properly. They have also uncovered evidence that an analogous protein may exist in people and may be associated with problems such as cleft lip, or premature ovarian failure. As they work together to form body parts, cells in developing organisms communicate like workers at a construction site. The discovery of a new signaling molecule in flies by Brown...


Word of the Day
baudekin
  • A rich embroidered or brocaded silk fabric woven originally with a warp of gold thread.
'Baudekin' seems to be an alternative form of 'baldachin,' from the Italian 'Baldacco,' Baghdad, the city where the material was made.
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