Latest Hedgehog signaling pathway Stories
Investigators have demonstrated for the first time that the most common malignant childhood brain tumor, medulloblastoma, is actually several different diseases, each arising from distinct cells destined to become different structures.
Miss Marple notwithstanding, arsenic might not be many people's favorite chemical.
Nearly all mammalian cells have what's called a primary cilium â€” a single, stump-like rod projecting from the smooth contours of the cell's outer membrane.
Researchers from St. Jude Children's Research Hospital and the Pediatric Brain Tumor Consortium (PBTC) presented at the American Society of Clinical Oncology the findings of a pediatric brain tumor study using an experimental drug that targets the underlying genetic makeup of the tumor.
CHICAGO, June 5 /PRNewswire/ -- Researchers from St.
Sonic hedgehog, a gene that plays a crucial rule in the positioning and growth of limbs, fingers and toes, has been confirmed in an unexpected place in the embryos of developing mice â€” the layer of cells that creates the skin.
Researchers have found a new oncogenic signaling pathway by which the environmental toxin arsenic may lead to adverse health effects, including bladder cancer. These study results are published in Cancer Research, a journal of the American Association for Cancer Research.
The role that the master gene Math1 plays in making a critical population of cells called granule neurons in the cerebellum also points to its involvement in the development of a common childhood brain tumor called medulloblastoma.
The laboratory of Dr. FrÃ©dÃ©ric Charron, a researcher at the Institut de recherches cliniques de MontrÃ©al (IRCM), has discovered a new molecular mechanism that permits the guidance of visual nerves towards the brain.
Genetic variations in the Sonic Hedgehog pathway increase the likelihood of recurrence, reduce survival time and limit response to therapy for people with non-muscle invasive bladder cancer.
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