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Latest Helices Stories

2012-02-14 14:36:26

Molecule is important step along the path to someday creating drugs that can go after rogue DNA directly Chemists at The University of Texas at Austin have created a molecule that's so good at tangling itself inside the double helix of a DNA sequence that it can stay there for up to 16 days before the DNA liberates itself, much longer than any other molecule reported. It's an important step along the path to someday creating drugs that can go after rogue DNA directly. Such drugs would...

2012-02-10 15:28:09

A research group in the Faculty of Medicine & Dentistry at the University of Alberta is hoping its latest discovery could one day be used to develop new therapies that target certain types of cancers. The discovery by Mark Glover, his graduate student Zahra Havali-Shahriari and post-doctoral fellow Nicolas Coquelle has shed light on what happens in cells when DNA is damaged. They solved the structure of a DNA repair enzyme called polynucleotide kinase/phosphatase, or PNKP. This allows...

2012-02-09 10:46:32

It's been more than 50 years since James Watson and Francis Crick showed that DNA is a double helix of two strands that complement each other. But how does a short piece of DNA find its match, out of the millions of 'letters' in even a small genome? New work by researchers at the University of California, Davis, handling and observing single molecules of DNA, shows how it's done. The results are published online Feb. 8 by the journal Nature. Defects in DNA repair and copying are strongly...

2012-01-20 10:54:13

New research published in BioMed Central's open access journal Cell & Bioscience is the first to show that left-handed Z-DNA, normally only found at sites where DNA is being copied, can also form on nucleosomes. The structure of DNA which provides the blueprint for life has famously been described as a double helix. To save space inside the nucleus, DNA is tightly wound around proteins to form nucleosomes which are then further wound and compacted into chromatin, which is further...

2012-01-18 21:38:03

A novel technique has been developed and demonstrated at Penn State University to map the proteins that read and regulate chromosomes -- the string-like structures inside cells that carry genes. The specific order in which these proteins attach DNA-containing nucleosomes along the chromosome determines whether a brain cell, a liver cell, or a cancer cell is formed. Until now, it has been exceedingly difficult to determine exactly where such proteins bind to the chromosome, and therefore how...

2012-01-05 16:37:59

In an effort to make data storage more cost-effective, a group of researchers from National Tsing Hua University in Taiwan and the Karlsruhe Institute of Technology in Germany have created a DNA-based memory device that is "write-once-read-many-times" (WORM), and that uses ultraviolet (UV) light to make it possible to encode information. The device, described in a paper accepted to the AIP's Applied Physics Letters, consists of a thin film of salmon DNA that has been embedded with silver...


Latest Helices Reference Libraries

Brief Introduction To DNA Probes
2014-01-12 00:00:00

DNA probes help scientists to detect a specific gene in a long DNA sequence. According to Dr. Michael A. Pfaller, DNA probes are “single-stranded pieces of nucleic acid, labeled with a specific tracer (isotope, enzyme, or chromophore), that will hydrogen bond (hybridize) with complementary single-stranded pieces of DNA (or RNA) under the appropriate conditions of pH, temperature, and iconic strength.” The Foundation for Genomics and Population Health website has a helpful video about...

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Word of the Day
toccata
  • In music, a work for a keyboard-instrument, like the pianoforte or organ, originally intended to utilize and display varieties of touch: but the term has been extended so as to include many irregular works, similar to the prelude, the fantasia, and the improvisation.
This word is Italian in origin, coming from the feminine past participle of 'toccare,' to touch.
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