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Latest Helmholtz Centre for Infection Research Stories

Genetic Defect Protects Mice From Infection With Influenza Viruses
2013-12-06 11:52:48

Helmholtz Centre for Infection Research A new study published in the scientific journal PLOS Pathogens points out that mice lacking a protein called Tmprss2 are no longer affected by certain flu viruses. The discovery was made by researchers from the Helmholtz Centre for Infection Research (HZI) in Braunschweig in collaboration with colleagues from Göttingen and Seattle. Whether it is H1N1, H5N1 or H7N9: The flu virus influenza A exists in many different types as its two coating...

Scientists Unravel The Role Of A Pathogen Molecule
2013-11-08 09:10:24

Helmholtz Centre for Infection Research Braunschweig have now discovered what makes a specific strain of Yersinia pseudotuberculosis–one of the main instigators for these infections–so dangerous: the bacteria produce a molecule called CNFy that facilitates the infection process for them. It changes the host cells in a manner that enables the injection apparatus of Yersinia, which injects toxins into the cells, to work more efficiently. This strengthens the infection and leads to...

2012-11-30 16:06:17

Molecule called IKBNS in charge of regulatory immune cell maturation Now, scientists at the Helmholtz Centre for Infection Research (HZI) have looked into the origin of Tregs and uncovered a central role played by the protein IkBNS. Armed with this knowledge, the researchers hope to manipulate Tregs in order to either inhibit or activate the immune system. Biochemist Prof. Ingo Schmitz and his team have now published their findings in the scientific journal Immunity. The immune system...

2012-11-15 11:36:10

Influenza curbs part of the immune system and abets bacterial infections When infected with influenza, the body becomes an easy target for bacteria. The flu virus alters the host's immune system and compromises its capacity to effectively fight off bacterial infections. Now, a team of immunologists at the Helmholtz Centre for Infection Research (HZI) and cooperation partners has discovered that an immune system molecule called TLR7 is partly to blame. The molecule recognizes the viral...

Body's Own Recycling System
2012-10-12 11:19:21

Researchers discover "molecular emergency brake" in charge of regulating self-digestion Times of distress literally eat away at the core of starving cells: They start to digest their own parts and recycle them for metabolic purposes. This process — called autophagy — also plays a role in immune defense. In that context, however, the digestive machinery is switched on for an entirely different purpose: the elimination of pathogens that have invaded the body. Now, Prof. Ingo...

2012-06-28 22:22:36

Researchers probe origin of optimized antibodies against infections An organism's ability to make new antibodies and use them to optimize its own immune defenses is of central importance in the fight against pathogens. In the case of severe infections, the overall relative speed with which an immune response proceeds could mean the difference between life and death. An international team of scientists, among them systems immunologist Prof. Michael Meyer-Hermann of the Helmholtz Centre for...

2010-10-05 15:09:33

New method will simplify study and treatment of diseases Therapeutic antibodies can be an efficient alternative when common drugs do not work anymore. However, antibodies obtained from blood of animals such as mice could not be used: The human immune system recognizes them as foreign and rejects them. In an international cooperation, scientists from the Helmholtz Centre for Infection Research (HZI) in Braunschweig, Germany have now succeeded in developing a promising approach to solve this...

2009-07-20 10:26:53

Researchers from Helmholtz Center for Infection Research, Germany, decipher special role of the messenger Beta-interferon for immune responses Researchers from the Molecular Immunology group at the Helmholtz Centre for Infection Research (HZI) in Braunschweig, Germany have now shown that Beta-Interferon also plays a crucial role during an immune response: without Beta-Interferon immune cells are unable to show "wanted posters" of pathogens to other cells. As a consequence, these cells will...

534943865a0d33e5c6cceadadbdc6f231
2008-06-25 14:26:59

Mild environmental conditions are a prerequisite for life. Strong acids or dissolved metallic salts in high concentrations are detrimental to both humans and to simpler life forms, such as bacteria. Such conditions destroy proteins, ensuring that all biological functions in the cells come to a standstill. So what do we find at the limits of hostile conditions where we still find life? Scientists at the Helmholtz Centre for Infection Research (HZI) in Braunschweig (Germany) have joined up with...


Word of the Day
cenobite
  • One of a religious order living in a convent or in community; a monk: opposed to anchoret or hermit (one who lives in solitude).
  • A social bee.
This word comes from the Latin 'coenobium,' convent, which comes from the Greek 'koinobios,' living in community.
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