Latest Hematopoietic stem cell transplantation Stories

Results Emphasize Immune Component of Autism Spectrum Disorder TRUMBULL, Conn., March 19, 2012 /PRNewswire-USNewswire/ -- A paper published online in Nature describes the results of using bone marrow transplant (BMT) to replace faulty immune system cells in models of Rett Syndrome. The procedure arrested many severe symptoms of the childhood disorder, including abnormal breathing and movement, and significantly extended the lifespan of Rett mouse models. Exploring the function of...

Infants with Batten disease, a rare but fatal neurological disorder, appear healthy at birth. But within a few short years, the illness takes a heavy toll, leaving children blind, speechless and paralyzed. Most die by age 5. There are no effective treatments for the disease, which can also strike older children. And several therapeutic approaches, evaluated in mouse models and in young children, have produced disappointing results. But now, working in mice with the infantile form of...

Researchers have identified a molecule that helps control the severity of graft-versus-host disease, a life-threatening complication for many leukemia patients who receive a bone-marrow transplant. The study, led by researchers with the Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James), used an animal model and tissues from human patients to show that high levels, or over-expression, of a...

Organ transplant patients usually spend a lifetime on expensive and often dangerous anti-rejection drugs. But experts have announced that such drugs may not even be needed in the future, thanks to a new study that suggests patients receiving an organ that is less than a perfect match can be protected against rejection by a second transplant of the donor’s imperfectly matched stem cells. The study is being hailed as a game-changer for transplantation. Experts announced the success of...

HOUSTON, March 8, 2012 /PRNewswire/ -- Bellicum Pharmaceuticals, Inc. today announced that it has raised $20 million in a Series B financing. The funding will be used to advance its lead CaspaCIDe(TM) and DeCIDe(TM) programs through Phase 2 clinical development. The additional funding strengthens Bellicum's balance sheet with $26 million of committed capital, including a $6.1 million award from the Cancer Prevention and Research Institute of Texas (CPRIT). Current and new investors...

First-of-its-kind study where donor, recipient are not related or immunologically matched CHICAGO, March 7, 2012 /PRNewswire-USNewswire/ -- New ongoing research published today in the journal Science Translational Medicine suggests organ transplant recipients may not require anti-rejection medication in the future thanks to the power of stem cells, which may prove to be able to be manipulated in mismatched kidney donor and recipient pairs to allow for successful transplantation...

(Ivanhoe Newswire) – It’s a disease that affects up to 3, 000 people each year and for sufferers of myelofibrosis, bone pain, bruising and fatigue are just some of the symptoms they live with every day. But now a new drug is changing the game. Myelofibrosis is caused by the accumulation of malignant bone marrow cells that triggers an inflammatory response, scarring the bone marrow and limiting its ability to produce blood, resulting in anemia. People who have myelofibrosis live on...

NEW YORK, Feb. 27, 2012 /PRNewswire/ -- Help Remedies® announces the launch of help I've cut myself & I want to save a life, which supplements Help's standard adhesive bandages with a bone marrow donor registry kit. By linking registry to a simple action, Help® hopes to reduce barriers to donation and find matches for some of the 10,000 people in the U.S. who need bone marrow transplants each year. (Photo: http://photos.prnewswire.com/prnh/20120227/NY60167 ) While Help...

New hematopoietic stem cell transplant program in Scottsdale, Ariz. offers treatment for blood cancers SCOTTSDALE, Ariz., Feb. 24, 2012 /PRNewswire-USNewswire/ -- The Virginia G. Piper Cancer Center at Scottsdale Healthcare announced today it has added a hematopoietic stem cell (HSC) transplant cancer treatment program (a/k/a bone marrow transplant) through its new Cancer Transplant Institute. Leaders of the new cancer treatment program expect it to attract transplant patients...

SAN BRUNO, Calif., Feb. 16, 2012 /PRNewswire/ -- Cord Blood Registry (CBR) is the exclusive partner for a growing number of clinical researchers focusing on the use of a child's own cord blood stem cells to help treat pediatric brain injury and acquired hearing loss. To ensure consistency in cord blood stem cell processing, storage and release for infusion, three separate trials have included CBR in their FDA-authorized protocol--including two at the University of Texas Health...