Latest hemoglobin Stories

Italian scientists pioneering a new gene transfer treatment for the blood disorder β-thalassemia have successfully completed preclinical trials, claiming they can correct the lack of beta-globin (ß-globin) in patients' blood cells which causes the disease. The research, published in EMBO Molecular Medicine, reveals how gene therapy may represent a safe alternative to current cures that are limited to a minority of patients.The disorder β-thalassemia, also known as Cooley's anemia, is...

A retired but well-preserved mechanism for regulating viruses that has worked its way into the human genome appears to modulate a switch between adult and fetal hemoglobin production, Medical College of Georgia researchers report.That switch could be the key to more targeted therapies for sickle cell patients whose misshaped adult hemoglobin hinders its ability to deliver oxygen throughout the body. Fetal hemoglobin, on the other hand, can't take on the dysfunctional sickle shape.After...

Having discovered a dramatic increase of an easy-to-detect enzyme in the red blood cells of people with diabetes and prediabetes, Johns Hopkins scientists say the discovery could lead to a simple, routine test for detecting the subtle onset of the disease, before symptoms or complications occur and in time to reverse its course.Pilot studies, published online April 22 in Diabetes, show the enzyme O-GlcNAcase is up to two to three times higher in people with diabetes and prediabetes than in...

A new study has found that the ethnic Tibetans' adaptation to high altitude occurred less than 3,000 years ago. Scientists at the University of California, Berkeley compared the genomes of 50 Tibetans and 40 Han Chinese.  They uncovered over 30 genes with DNA mutations that have become more prevalent in Tibetans than Han Chinese, about half of which are related to how the body uses oxygen. One mutation spread from fewer than 10 percent of the Han Chinese to nearly 90 percent of all...

IRVINE, Calif., June 28 /PRNewswire-FirstCall/ -- Masimo (Nasdaq: MASI), the inventor of Masimo Rainbow Pulse CO-Oximetry(TM), Masimo Rainbow Acoustic Monitoring(TM), and Masimo SET® Measure-Through Motion and Low Perfusion pulse oximetry, today announced FDA 510(k) clearance for the Pronto-7(TM)--a new handheld device designed for quick and easy noninvasive hemoglobin (SpHb®) spot-check testing, along with SpO2, pulse rate, and perfusion index, in virtually any environment. (Photo:...

IRVINE, Calif., June 23 /PRNewswire-FirstCall/ -- Masimo (Nasdaq: MASI), the inventor of Rainbow Pulse CO-Oximetry(TM), Rainbow Acoustic Monitoring(TM), and Masimo SET® Measure-Through Motion and Low Perfusion pulse oximetry, today announced the international limited market release of Masimo Pronto-7 -- a new handheld device designed for quick and easy noninvasive hemoglobin (SpHb®) spot-check testing in virtually any environment. As part of the limited market release, select...

IRVINE, Calif., June 16 /PRNewswire-FirstCall/ -- Masimo (Nasdaq: MASI), the inventor of Pulse CO-Oximetry(TM) and Measure-Through Motion and Low Perfusion pulse oximetry, announced today that a new independent study demonstrating the clinical accuracy of Masimo noninvasive and continuous hemoglobin (SpHb) monitoring was presented this week at the European Society of Anaesthesiology (ESA) Annual Congress in Helsinki, Finland. In the study, titled "Comparison Between a New Noninvasive...

A new study pinpoints the genetic changes that enable Tibetans to thrive at altitudes where others get sick.In the online edition of Proceedings of the National Academy of Sciences, an international team has identified a gene that allows Tibetans to live and work more than two miles above sea level without getting altitude sickness.A previous study published May 13 in Science reported that Tibetans are genetically adapted to high altitude. Now, less than a month later, a second study by...

EMBL scientists identify molecules that ensure red blood cell productionRed blood cells, the delivery men that take oxygen to cells all around the body, have short lives. To keep enough of them in circulation, the human body produces around 2 million of these cells every second "“ even more in response to challenges like severe blood loss. In a study published today in the Journal of Experimental Medicine, scientists at the European Molecular Biology Laboratory (EMBL) in Monterotondo,...

PHILADELPHIA, May 26 /PRNewswire-USNewswire/ -- Complex wounds affect more patients in the United States than heart attack and stroke combined. About 150,000 amputations a year result from complex wounds, while about 80,000 are attributed to diabetes and peripheral arterial disease. There are currently no established methods for early detection of wound healing, or for precise identification of healing progress. A new device developed by researchers can change chronic wound management....