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Latest hemoglobin Stories

2011-11-02 09:09:31

Laboratory study at University of Michigan Health System shows increasing TR2/TR4 expression can lead to higher fetal hemoglobin levels in sickle cell patients A University of Michigan Health System laboratory study reveals a key trigger for producing normal red blood cells that could lead to a new treatment for those with sickle cell disease. The study, conducted in mice, appears in this week's early edition of the Proceedings of the National Academy of Sciences, and holds promise for...

2011-10-21 13:51:19

Professor Qin Wenbin from BaoTou Medical College first identified the hemoglobin (Hb) A2 phenomenon 30 years ago. His first paper on this phenomenon was published in Acta Biochimica et Biophysica Sinica, in Chinese, in 1981. Subsequent research investigating its mechanism was published in Chinese in the Chinese Biochemical Journal and Progress in Biochemistry and Biophysics in 1991 and more recently in Electrophoresis, in 2010. Using electrophoretic methods, he discovered that Hb is...

Scientists Discover New Possible Therapy For Sickle Cell Anemia
2011-10-14 06:12:19

Scientists, funded by the National Institutes of Health, have discovered a way to turn on the mechanism that creates fetal hemoglobin. Fetal hemoglobin is in the human body during the fetal stage of life up to around 3 to 6 months after birth. Scientists have known for years that increased levels of fetal hemoglobin reduce the onset of the misshapen blood cells that cause the symptoms of sickle cell anemia; symptoms include pain, strokes, organ dysfunction and premature death. The...

2011-10-03 22:56:52

Researchers at St. Michael's Hospital have discovered a new function for an enzyme that may protect against organ injury and death from anemia. "Identifying this mechanism may lead to new therapies and approaches to improving outcomes for anemic patients," said Dr. Greg Hare, a researcher at the Li Ka Shing Knowledge Institute of the hospital and one of the lead investigators of the study. One in four people around the world and up to 50 per cent of patients coming for surgery are...

2011-09-29 09:22:43

Using a patient´s own stem cells, researchers at Johns Hopkins have corrected the genetic alteration that causes sickle cell disease (SCD), a painful, disabling inherited blood disorder that affects mostly African-Americans. The corrected stem cells were coaxed into immature red blood cells in a test tube that then turned on a normal version of the gene. The research team cautions that the work, done only in the laboratory, is years away from clinical use in patients, but should...

2011-09-27 15:02:32

Researchers at the Perelman School of Medicine at the University of Pennsylvania, Monash University, and Virginia Tech have used a set of novel inhibitors to analyze how the malaria parasite, Plasmodium falciparum, uses enzymes to chew up human hemoglobin from host red blood cells as a food source. They have validated that two of these parasite enzymes called peptidases are potential anti-malarial drug targets. The research appeared in the Aug. 15 early online issue of the Proceedings of the...

2011-09-22 11:08:42

More public awareness and education about sickle cell disease, an inherited disease that affects the blood system, is critically important, said a renowned hematologist from Baylor College of Medicine and Texas Children's Hospital. Dr. Russell E. Ware, professor of pediatrics at BCM, director of the Texas Children's Center for Global Health and director of the Texas Children's Hematology Center, offered information on the disease, what causes it, how it is treated and living with sickle...

Woolly Mammoth Could Give Clues Toward New Artificial Blood For Humans
2011-09-15 07:16:00

  The blood from woolly mammoths–those extinct elephant-like creatures that roamed the Earth in pre-historic times–is helping scientists develop new blood products for modern medical procedures that involve reducing patients' body temperature. The report appears in ACS' journal Biochemistry. Chien Ho and colleagues note that woolly mammoth ancestors initially evolved in warm climates, where African and Asian elephants live now, but migrated to the cold regions of...


Word of the Day
call-note
  • The call or cry of a bird or other animal to its mate or its young.
'Call-note' is newer than 'bird-call,' which originally referred to 'an instrument for imitating the note of birds' but now also refers to 'the song or cry of a bird.'
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