Latest Hemophagocytic Lymphohistiocytosis Stories

2011-05-16 18:26:17

Children's Hospital of Philadelphia study in animals: Immune system proteins might protect children from rare, deadly inflammation By analyzing complex interactions of the immune system in an animal study, pediatric researchers have found potential tools for controlling a life-threatening condition called a cytokine storm that may strike children who have juvenile arthritis and other autoimmune diseases. In a cytokine storm, the body's immune system rages out of control, resulting in...

2010-12-16 11:53:00

HOUSTON, Dec. 16, 2010 /PRNewswire-USNewswire/ -- December marks the 10-year anniversary of the formation of the world-renowned Histiocytosis Program at Texas Children's Cancer Center and Hematology Service (TCCC&HS), a joint center of Texas Children's Hospital and Baylor College of Medicine. Histiocytic Diseases, disorders of the immune system that are difficult to diagnose and define, include Langerhans Cell Histiocytosis (LCH), Hemophagocytic Lymphohistiocytosis (HLH) and other even...

2010-02-26 09:56:51

A new University of Colorado at Boulder study shows mice infected with the bacteria salmonella develop clinical signs consistent with a deadly and poorly understood human inflammatory disease, a finding that may lead to new therapies. The human disease, known as Hemophagocytic Lymphohistiocytosis, or HLH, is a rare inflammatory disease that kills between 50 percent and 90 percent of its victims, said Diane Brown, lead author of the study. HLH treatment may require bone marrow transplantation,...

2009-11-03 13:25:21

Familial hemophagocytic lymphohistiocytosis (FHL) is an inherited, fatal, immune disorder characterized by uncontrolled activation of immune cells known as lymphocytes and macrophages. Disease-causing mutations have been identified in several genes that generate proteins involved in lymphocyte-mediated cell death, including syntaxin-11. Now, Genevive de Saint Basile and colleagues, at INSERM U768, France, have added a new gene to this list by determining that two distinct mutations in the...

2008-08-27 12:01:29

By Eric Kurhi In the driver's seat of his miniature orange NASCAR-style racer, little Stephon Cinsear Williams is hell on wheels. The 3- 1/2 -year-old owned the outdoor pathways in front of his apartment in the Hayward foothills, ramming through plastic toys and nearly running over his mother's toes. "He's getting into everything," said Nicole Williams, 24. "He's just been so happy to be back from the hospital." The boy, who goes by the name Cinsear, just came back Monday after his...

2006-03-01 19:10:00

By Patricia Reaney LONDON -- A chemotherapy treatment given to patients with an immune system disorder may work for human avian influenza, but it has not been tested in patients, researchers said on Thursday. Dr Jan-Inge Henter of the Karolinska Hospital in Stockholm said at the moment it was a theory. But he and colleagues in Hong Kong believe chemotherapy treatment could work because of the similarities between human infection with H5N1 bird flu and an illness known as haemophagocytic...

Word of the Day
  • A small crescent-shaped structure or marking, especially the white area at the base of a fingernail that resembles a half-moon.
This word is a diminutive of the Latin 'luna,' moon.