Quantcast
Last updated on April 24, 2014 at 5:22 EDT

Latest Hepatocyte Stories

2010-10-12 12:41:00

CHARLOTTESVILLE, Va., Oct. 12 /PRNewswire/ -- Beta-Pro LLC, announced today that it has expanded its operations to accommodate increasing demands from pharmaceutical drug discovery and research institutes in the $2 billion hepatocyte market. The human cellular sciences company now manages extensive laboratory facilities in the University of Virginia Research Park in Charlottesville, Virginia. "Beta-Pro has already established a foothold in the human pancreatic islet cell market and has...

2010-09-10 15:41:00

CHICAGO, Sept. 10 /PRNewswire/ -- Celsis In Vitro, Inc. (Celsis IVT) announced today that the United States District Court for the Northern District of Illinois in Chicago has entered a preliminary injunction against CellzDirect Inc., Invitrogen Corporation, and Life Technologies (the Defendants) due to their infringement of U.S. Patent No. 7,604,929 (the Liverpool(TM) patent). Life Technologies of Carlsbad, California (Nasdaq: LIFE) is the parent of Invitrogen and CellzDirect. The...

2010-06-14 14:20:05

Discarded livers have potential to be reengineered into usable replacement organs A team led by researchers from the Center for Engineering in Medicine at Massachusetts General Hospital (MGH) has developed a technique that someday may allow growth of transplantable replacement livers. In their report that will be published in Nature Medicine and is receiving early online release, the investigators describe using the structural tissue of rat livers as scaffolding for the growth of tissue...

2010-02-01 13:04:43

A research team from the National Taiwan University Hospital has evaluated the efficiency of transplanted hepatocyte (liver) cells in animal models severely damaged by two kinds of chemical toxicity to see whether and how transplanted hepatocytes were able to efficiently repopulate the toxin-induced, severely damaged livers. The results of this study are published in the current double issue of Cell Transplantation (18:10/11) and are freely available on-line at...

2009-11-18 14:39:05

Embryonic stem (ES) cells, known for their capacity to proliferate indefinitely and differentiate into almost all types of cells including hepatocytes, have raised the hope of cellular replacement therapy for liver failure. There have been several protocols available for hepatic fate specification from ES cells, however, most of the protocols currently used result in low yield or purity of functional hepatocytes. Valproic acid (VPA), a histone deacetylase inhibitor, has been demonstrated to...

2009-10-20 17:37:27

Scientists have for the first time produced liver cells from adult skin cells using the induced pluripotent stem cell technology Scientists have for the first time produced liver cells from adult skin cells using the induced pluripotent stem cell (iPSC) technology. The study, led by the University of Edinburgh's MRC Centre for Regenerative Medicine, paves the way for the creation of a stem cell library that can be used for in vitro hepatic disease models. Presently primary human hepatocytes...

2009-10-13 09:05:00

CHIBA, Japan, Oct. 13 /PRNewswire/ -- Transparent, Inc., a bio-venture business headquartered here, announced today that it will be introducing Cell-able (http://www.cell-able.com), a human hepatocyte array kit that has the potential to reduce drug development costs and time-to-market for pharmaceutical companies, at its exhibit at the annual meeting of the International Society for the Study of Xenobiotics (www.issx.org ) in Baltimore, Maryland, October 18-22. It is estimated that...

fd3f2f9fab9447dccb5065c519fdef03
2009-10-10 11:14:43

A combination of bioengineering and medical research at the University of California, San Diego has led to a new discovery that could pave the way for more effective treatments for liver disease. In this work, the researchers have utilized an array system that can identify the biological components that can lead to or alleviate liver disease. The technology works by controlling the range of environments surrounding star-shaped liver cells called hepatic stellate cells (HSCs). HSCs are the...

2009-09-07 19:41:17

Drug toxicity testing may improve because a new process helps keep cultured liver cells alive, U.S. researchers suggest. The report, published in Proceedings of the National Academy of Sciences, describes how liver cells grown in a high-oxygen environment and in a culture medium free of animal-derived serum quickly began to function as they did within the liver. Finding a better way to culture liver cells has been a major stumbling block in the development of predictive drug-discovery tools,...

2009-09-02 10:02:03

Mass. General-developed strategy dramatically improves function of cultured liver cells A team led by Massachusetts General Hospital (MGH) researchers has developed an innovative way to culture liver cells for drug toxicity screening. In a report to be published in Proceedings of the National Academy of Sciences that has been released online, the investigators describe how liver cells grown in a high-oxygen environment and in a culture medium free of animal-derived serum quickly begin to...