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Latest Hepcidin Stories

2014-08-27 12:30:15

WASHINGTON, Aug. 27, 2014 /PRNewswire-USNewswire/ -- An experimental drug designed to help regulate the blood's iron supply shows promise as a viable first treatment for anemia of inflammation, according to results from the first human study of the treatment published online today in Blood, the Journal of the American Society of Hematology (ASH). Anemia is a condition that occurs when red blood cells are in short supply or do not function properly. When an individual has anemia,...

2014-05-19 11:45:34

European Society of Cardiology Negative iron balance predicts survival in patients with acute heart failure, according to research presented for the first time today at the Heart Failure Congress 2014 in Athens, Greece. The Congress is the main annual meeting of the Heart Failure Association of the European Society of Cardiology. Professor Ewa Jankowska, first author of the study, said: "Patients with acute heart failure have a major collapse in homeostasis. Iron is a key micronutrient...

2013-12-18 13:33:05

A UCLA research team has found no evidence of an association between iron levels in the body and the risk of atherosclerosis, the hardening and narrowing of the arteries that leads to cardiovascular disease, the No. 1 killer in the U.S. The discovery, based on a comprehensive study in a mouse model of atherosclerosis, contradicts a long-held hypothesis about the role of iron in the disease and carries important implications for patients with chronic kidney disease or anemia related to...

2011-11-16 09:37:40

Researchers at Emory University School of Medicine have identified hepcidin, a hormone that regulates iron levels in the body, as a potential target for treating atherosclerosis. Suppressing hepcidin is a way to reduce the iron levels inside the white blood cells found in arterial plaques. Reducing iron levels pushes those cells to clean up harmful cholesterol in a process called "reverse cholesterol transport," interfering with atherosclerosis, researchers have found. The data is being...

2011-11-01 21:11:53

Multiple organs, including the liver and the heart, become damaged if an individual has an excessive amount of iron in their body. Treatments for iron overload are arduous and/or have severe side effects. A team of researchers led by Elizabeta Nemeth, at the University of California, Los Angeles, has now generated data in mice that suggest that they have designed a promising new approach to reducing iron overload. Iron overload is a hallmark of the genetic disease hereditary...

2011-11-01 21:09:49

Iron overload is a common condition affecting millions of people worldwide. Excess iron in the body is toxic, and deposits can cause damage to the liver, heart and other organs. Current treatments, researchers say, are not ideal and have significant side effects. Iron in the body is regulated by a hormone called hepcidin, and a deficiency in this hormone can cause the iron overload seen in genetic disorders like hereditary hemochromatosis and Cooley's anemia. In the hopes of finding a...

2011-09-26 15:19:13

Researchers at Wake Forest Baptist Medical Center have made a discovery that brings them one step closer to being able to better predict which patients have the best chance of surviving breast cancer. The group has identified 16 genes, or proteins, all involved in iron metabolism, that provide better prognostic information than conventional, standard markers of prognosis. Last summer, some of the same investigators published a study showing that women who had high levels of a protein...


Word of the Day
omadhaun
  • A fool; a simpleton: a term of abuse common in Ireland and to a less extent in the Gaelic-speaking parts of Scotland.
This word is partly Irish in origin.