Latest Herceptin Stories
Using Herceptin with chemotherapy, instead of after, clearly improves treatment of women with HER2+ breast cancer, and should be the new standard of care, says a Mayo Clinic researcher who led what is regarded to be a key clinical trial determining the best use of Herceptin.Patients using Herceptin and chemotherapy at the same time had a relative 25 percent reduction in the risk of recurrence of cancer or death, compared with women who used Herceptin after chemotherapy, says Edith Perez,...
Large study finds subset of women that may need additional therapyEarly-stage breast cancer patients with HER2 positive tumors one centimeter or smaller are at significant risk of recurrence of their disease, compared to those with early-stage disease who do not express the aggressive protein, according to a study led by researchers at The University of Texas M. D. Anderson Cancer Center.The findings, published Nov. 2 online in the Journal of Clinical Oncology, is the first large study to...
A team of Canadian cardiologists, in collaboration with oncologists, are playing an important role in the war against breast cancer Dr. Michael McDonald told the Canadian Cardiovascular Congress 2009, co-hosted by the Heart and Stroke Foundation and the Canadian Cardiovascular Society.At issue is how to use a highly effective drug therapy for early-stage breast cancer while maintaining the cardiovascular health of the patient. The drug "“ trastuzumab (herceptin) "“ inhibits cancer cell...
ORLANDO, Fla., May 18 /PRNewswire-USNewswire/ -- Combining two chemotherapy drugs with trastuzumab (Herceptin) to treat women who have metastatic HER2+ breast cancer may offer physicians another choice in their treatment options. At the 45th Annual Meeting of the American Society of Clinical Oncology (ASCO), researchers from the Mayo Clinic campus in Florida report that using a combination of capecitabine, vinorelbine, and trastuzumab offers a treatment option that is at least as...
Genentech/Roche/Chugai's Drug in Combination With Herceptin and Taxotere Will Become Decision Resources Gold Standard Regimen by 2017, According to a New Report from Decision Resources WALTHAM, Mass., Feb. 11 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that if Genentech/Roche/Chugai's Herceptin is approved in combination with emerging therapies, it will be in a position to retain patient share...
EAST HANOVER, N.J., Dec. 12 /PRNewswire/ -- New data from two early clinical studies show that RAD001(R) (everolimus) may overcome resistance to Herceptin(R) (trastuzumab)* in women with HER2-positive metastatic breast cancer. These results support the initiation of a Phase III clinical trial program to fully explore the potential of RAD001 (proposed brand name Afinitor(R)) in breast cancer. Two Phase I studies were presented today during the CTRC-AACR San Antonio Breast Cancer...
Monogram Biosciences, Inc. (Nasdaq:MGRM) today announced that additional EGFR/HER assays have been successfully tested in sets of fixed human tumors and are now available for use in drug development programs. These assays provide quantitative measurements of the HER2:HER3 heterodimer, and its associated downstream HER3:PI3K complex. An assay for p95, a truncated form of HER2, is in advanced development. These assays provide a measure of the activation state of key signaling pathways in tumors...
By Liz Szabo Barbara Bradfield has lived to see dramatic changes in breast cancer. When she was diagnosed in 1989, Bradfield's tumor -- which produced an overabundance of a protein called HER2 -- was considered especially deadly. Today, women with tumors like hers have some of the best survival rates in breast cancer. Experts say the drug that has kept Bradfield healthy for so long, Herceptin, has changed the nature of breast cancer and helped doctors better understand what causes the...
By EATON, Dan National has been forced to trim its election health pledges due to tough economic times. Policies shed include a costly $40 million insurance rebate for seniors, while questions remain about the fate of funding plans for breast cancer drug Herceptin and Plunketline. On the campaign trail yesterday at a Palmerston North medical centre, National leader John Key unveiled plans to fund 20 new elective surgery theatres and train 800 additional surgeons, anaesthetists and nurses...
SUCCESSFUL businesswoman Jacqueline Williams was getting ready for a trip to London and taking her normal morning shower before setting off. But that journey never took place. Instead it was the start of a far more harrowing journey that continues to this very day. For while she was in the bathroom Jacqueline discovered a lump in her breast and with the alarm bells ringing her next stop was a visit to her GP. A couple of hospital appointments followed and tests were taken before she was...
