Latest Histology Stories
New York University biologists have identified a new mechanism for regulating color vision by studying a mutant fly named after Frank ('Ol Blue Eyes) Sinatra. Their findings, which appear in the journal Nature, focus on how the visual system functions in order to preserve the fidelity of color discrimination throughout the life of an organism. They also offer new insights into how genes controlling color detection are turned on and off. Many biologists study how different cells develop to...
BRANFORD, Conn., Oct. 6, 2011 /PRNewswire/ -- HistoRx, the leader in quantitative immunohistochemistry, advances its proprietary position in digital pathology through the recent issuance of US patents covering key features necessary for achievement of reproducible, standardized image analysis results. The U.S. Patent and Trademark Office has granted two new patents protecting the company's methods for standardization of digital microscopy instruments, methods required to generate...
After more than three decades of research, University of Pennsylvania veterinarians and vision-research scientists, with associates at Cornell University, have identified a gene responsible for a blindness-inducing disease that afflicts dogs. In the process, the Penn scientists may have discovered clues about how retinal cells, and perhaps even neurons, can be regenerated. The research was conducted by Gustavo D. Aguirre, William A. Beltran, Agnes I. Berta and Sem Genini of Penn's School...
Combined with fluorescence labeling, new approach produces 3D images at unprecedented depth and levels of spatial detail Researchers at RIKEN, Japan's flagship research organization, have developed a ground-breaking new aqueous reagent which literally turns biological tissue transparent. Experiments using fluorescence microscopy on samples treated with the reagent, published this week in Nature Neuroscience, have produced vivid 3D images of neurons and blood vessels deep inside the...
Biologists and psychologists know that light affects mood, but a new University of Virginia study indicates that light may also play a role in modulating fear and anxiety.Psychologist Brian Wiltgen and biologists Ignacio Provencio and Daniel Warthen of U.Va.'s College of Arts & Sciences worked together to combine studies of fear with research on how light affects physiology and behavior.Using mice as models, they learned that intense light enhances fear or anxiety in mice, which are...
TUCSON, Ariz., July 26, 2011 /PRNewswire/ -- Ventana Medical Systems, Inc. (Ventana), a member of the Roche Group, announced today the launch of their OptiView DAB IHC Detection Kit, the first fully-automated immunohistochemistry (IHC) detection kit that combines both sensitive chemistry and flexible software to deliver highly customizable staining. OptiView Detection significantly enhances stain quality, allowing pathologists to view IHC assays more clearly than ever before. (Photo:...
Johns Hopkins researchers uncover the source of the visual system's 'false alarms'On rare occasion, the light-sensing photoreceptor cells in the eye misfire and signal to the brain as if they have captured photons, when in reality they haven't. For years this phenomenon remained a mystery. Reporting in the June 10 issue of Science, neuroscientists at the Johns Hopkins University School of Medicine have discovered that a light-capturing pigment molecule in photoreceptors can be triggered by...
Creatures are not born hardwired to see. Instead, they depend on electrical activity in the retina to refine the complex circuits that process visual information. Two new studies from Brown University in different species using different techniques show how nascent animal brains use light to wire up or construct their central vision system.Any parent knows that newborns still have a lot of neurological work to do to attain fully acute vision. In a wide variety of nascent animals, genes...
FREDERICK, Md., May 31, 2011 /PRNewswire/ -- SAIC-Frederick, Inc. and Biomatrica have begun a technology collaboration to improve molecular analysis of tumors, which is becoming increasingly important in cancer research and in the design of the next generation of targeted therapies. The two organizations will focus on developing better processes to isolate nucleic acids from tumor samples collected by pathologists in the clinic. Preserving nucleic acids, particularly RNA, is important for...
In this month's Physics World, Richard Taylor, professor of physics, psychology and art at the University of Oregon, warns that artificial retinal implants "“ a technology fast becoming a reality "“ must adapt to the unique features of the human eye in order to become an effective treatment.The gap between digital camera technology and the human eye is getting ever smaller, in terms of both the number of light-sensitive detectors and the space that they occupy. A human retina typically...
