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Latest Histology Stories

New Chemical Reagent Turns Mouse Brain Transparent
2011-08-31 12:13:45

  Combined with fluorescence labeling, new approach produces 3D images at unprecedented depth and levels of spatial detail Researchers at RIKEN, Japan's flagship research organization, have developed a ground-breaking new aqueous reagent which literally turns biological tissue transparent. Experiments using fluorescence microscopy on samples treated with the reagent, published this week in Nature Neuroscience, have produced vivid 3D images of neurons and blood vessels deep inside...

2011-08-11 12:01:53

Biologists and psychologists know that light affects mood, but a new University of Virginia study indicates that light may also play a role in modulating fear and anxiety. Psychologist Brian Wiltgen and biologists Ignacio Provencio and Daniel Warthen of U.Va.'s College of Arts & Sciences worked together to combine studies of fear with research on how light affects physiology and behavior. Using mice as models, they learned that intense light enhances fear or anxiety in mice, which are...

2011-07-26 07:00:00

TUCSON, Ariz., July 26, 2011 /PRNewswire/ -- Ventana Medical Systems, Inc. (Ventana), a member of the Roche Group, announced today the launch of their OptiView DAB IHC Detection Kit, the first fully-automated immunohistochemistry (IHC) detection kit that combines both sensitive chemistry and flexible software to deliver highly customizable staining. OptiView Detection significantly enhances stain quality, allowing pathologists to view IHC assays more clearly than ever before. (Photo:...

2011-06-09 23:50:49

Johns Hopkins researchers uncover the source of the visual system's 'false alarms' On rare occasion, the light-sensing photoreceptor cells in the eye misfire and signal to the brain as if they have captured photons, when in reality they haven't. For years this phenomenon remained a mystery. Reporting in the June 10 issue of Science, neuroscientists at the Johns Hopkins University School of Medicine have discovered that a light-capturing pigment molecule in photoreceptors can be triggered by...

2011-06-06 15:28:46

Creatures are not born hardwired to see. Instead, they depend on electrical activity in the retina to refine the complex circuits that process visual information. Two new studies from Brown University in different species using different techniques show how nascent animal brains use light to wire up or construct their central vision system. Any parent knows that newborns still have a lot of neurological work to do to attain fully acute vision. In a wide variety of nascent animals, genes...

2011-05-31 06:00:00

FREDERICK, Md., May 31, 2011 /PRNewswire/ -- SAIC-Frederick, Inc. and Biomatrica have begun a technology collaboration to improve molecular analysis of tumors, which is becoming increasingly important in cancer research and in the design of the next generation of targeted therapies. The two organizations will focus on developing better processes to isolate nucleic acids from tumor samples collected by pathologists in the clinic. Preserving nucleic acids, particularly RNA, is important for...

2011-04-28 13:57:50

In this month's Physics World, Richard Taylor, professor of physics, psychology and art at the University of Oregon, warns that artificial retinal implants "“ a technology fast becoming a reality "“ must adapt to the unique features of the human eye in order to become an effective treatment. The gap between digital camera technology and the human eye is getting ever smaller, in terms of both the number of light-sensitive detectors and the space that they occupy. A human retina...

2011-03-29 07:00:00

EXTON, Pa., March 29, 2011 /PRNewswire/ -- Morphotek®, Inc., a subsidiary of Eisai Inc., announced today that it has entered into a collaboration and license agreement with Biocare Medical, LLC. Under the agreement, the parties will collaborate to develop and commercialize an immunohistochemical (IHC) diagnostic kit utilizing Morphotek's proprietary monoclonal antibody to specifically detect human folate receptor alpha (FRA) with Biocare's intelliPATH(TM) Automated...

2011-03-09 18:19:05

Retinal ganglion cells can recognize directions thanks to amacrine cells The properties of optical stimuli need to be conveyed from the eye to the brain. To do this efficiently, the relevant information is extracted by pre-processing in the eye. For example, some of the so-called retinal ganglion cells, which transmit visual information to the brain via the optic nerve, only react to light stimuli moving in a particular direction. This direction selectivity is generated by inhibitory...

2011-02-25 13:14:17

European Multidisciplinary Conference in Thoracic Oncology news An inexpensive and rapid testing method can effectively identify a sub-group of never-smoking lung cancer patients whose tumors express a molecule associated with increased risk of disease progression or recurrence, US researchers have found. Dr Ping Yang from the Mayo Clinic, Rochester, USA, and colleagues, reported the findings at the European Multidisciplinary Conference in Thoracic Oncology (EMCTO), 24-26 February 2011,...


Word of the Day
attercop
  • A spider.
  • Figuratively, a peevish, testy, ill-natured person.
'Attercop' comes from the Old English 'atorcoppe,' where 'atter' means 'poison, venom' and‎ 'cop' means 'spider.' 'Coppa' is a derivative of 'cop,' top, summit, round head, or 'copp,' cup, vessel, which refers to 'the supposed venomous properties of spiders,' says the OED. 'Copp' is still found in the word 'cobweb.'
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