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Last updated on April 16, 2014 at 1:21 EDT

Latest Histology Stories

2009-11-17 11:16:00

ROCKVILLE, Md., Nov. 17 /PRNewswire/ -- Expression Pathology, a leader in tissue proteomic analysis, today announced Mayo Clinic has licensed non-exclusive rights to Expression Pathology's Liquid Tissue® patent for use in diagnosis of systemic amyloidosis in formalin-fixed tissue. Patented Liquid Tissue® methodology enables solubilization of proteins for mass spectrometric analysis of formalin-fixed paraffin-embedded (FFPE) tissue, the standard form of...

2009-11-16 16:27:17

Determining what triggers the death of retinal cells, called photoreceptors, could hold the key to stopping blinding disorders caused by a wide range of eye diseases, Yale School of Medicine researchers report in the November journal Investigative Ophthalmology & Visual Science. Several blinding disorders are known to cause the breakdown of photoreceptors. Caroline Zeiss, associate professor of comparative medicine and ophthalmology at Yale School of Medicine, and her colleagues sought to...

2009-10-01 13:16:39

A German-Hungarian medical team says it has developed a mass spectrometric ionization technique that can analyze vital tissues during surgical procedures. The researchers, led by Zoltan Takats of Justus-Liebig University in Giessen, Germany, said the technique might make it possible to distinguish between malignant tumor cells and surrounding healthy tissue in real time during cancer surgery. Until now, precise histological examination of the removed tissue has occurred after tumor surgery...

2009-09-30 07:24:24

Coupling electrosurgery with mass spectrometry for real-time identification of tumor tissues Instead of the classic scalpel, surgeons can also operate with an electroscalpel. A significant advantage to this technique is that while a cut is being made, blood vessels are closed off and hemorrhaging eliminated. Now another advantage may be added as well: a German-Hungarian research team has developed a mass-spectrometry-based technique by which tissues can be analyzed during a surgical...

2009-08-27 14:50:09

Researchers led by Dr. Soheil Dadras at the Stanford University Medical Center have developed a novel methodology to extract microRNAs from cancer tissues. The related report by Ma et al, "Profiling and discovery of novel miRNAs from formalin-fixed paraffin-embedded melanoma and nodal specimens," appears in the September 2009 issue of the Journal of Molecular Diagnostics.Cancer tissues from patients are often stored by a method that involves formalin fixation and paraffin embedding to retain...

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2009-07-27 06:35:00

Researchers from the John Hopkins School of Medicine have discovered a new type of cell used for vision in fish.The report, which appears in the journal Nature, explains how researchers found a retinal horizontal cell that senses light and contributes to vision."This is mind-boggling," says King-Wai Yau, Ph.D., a professor of neuroscience at John Hopkins."For more than 100 years, it's been known that rod cells and cone cells are responsible for sensing light, and therefore, vision," says Yau....

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2009-07-23 14:00:00

A new study by scientists at the University of Iowa shows why muscle membranes don't rupture when healthy people exercise.The findings shed light on a mechanism that appears to protect cells from mechanical stress. The study, which appears online July 20-24 in Proceedings of the National Academy of Sciences (PNAS) Early Edition, also helps explain why muscle damage is so severe when this mechanism is disrupted, which occurs in certain congenital and limb-girdle muscular...

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2009-05-19 07:30:00

St. Jude study of the nocturnal owl monkey suggests that evolution needed only a few genetic changes to profoundly alter eye anatomy Researchers comparing the fetal development of the eye of the owl monkey with that of the capuchin monkey have found that only a minor difference in the timing of cell proliferation can explain the multiple anatomical differences in the two kinds of eyes. The findings help scientists understand how a structure as complex as the eye could change gradually through...

2009-04-22 17:52:00

DENVER, April 22 /PRNewswire/ -- Cambridge Research & Instrumentation, Inc. (CRi) introduced the Vectra(TM) Intelligent Slide Analysis System at the 100th Annual Meeting of the American Association for Cancer Research (AACR) in Denver. The Vectra system is the world's only multispectral brightfield- and fluorescence-capable solution for rapidly generating high-resolution cellular and tissue images from samples stained with standard H&E, immunohistochemical and immunofluorescence...

2009-04-17 11:25:08

The eyes of nocturnal mammals have very large numbers of highly-sensitive rod photoreceptors (the cell type responsible for night vision). They have to perceive light which is less than a millionth of the intensity of daylight. An international team headed by LMU researchers Dr. Boris Joffe, Dr. Irina Solovei and Professor Thomas Cremer has now succeeded in demonstrating that a nocturnal lifestyle and the challenges posed by it have a dramatic effect on the organisation of the nuclei of rod...