Latest Histone deacetylase Stories
SUNNYVALE, Calif., April 26, 2011 /PRNewswire/ -- Pharmacyclics, Inc.
BellBrook Labs has developed a new HTS assay for screening methyltransferases, the family of enzymes involved in epigenetic modifications that cause cancerous cell growth and metastasis.
Tumor suppressor genes normally control the growth of cells, but cancer can spring up when these genes are silenced by certain chemical reactions that modify chromosomes.
Scientists have achieved one of the oldest and most rarely achieved goals of cancer researchâ€”they have found a way to â€œdistractâ€ cancer cells from their normal activities and make them act like normal cells.
WALTHAM, Mass., March 31, 2011 /PRNewswire/ -- Syndax Pharmaceuticals, Inc., a clinical-stage epigenetics oncology company, today announced 11 posters on entinostat, an oral, highly selective, class I histone deacetylase (HDAC) inhibitor, will be presented at the 102nd Annual American Association for Cancer Research meeting April 2 to April 6 in Orlando, FL.
A paper announcing a breakthrough discovery in the fight against Niemann-Pick Type C, coauthored by Olaf Wiest and Paul Helquist of the University of Notre Dame's Department Chemistry & Biochemistry and Frederick Maxfield, Chair of Biochemistry at Cornell University Weill College of Medicine, appears in the Proceedings of the National Academy of Sciences this week.
The liver normally makes and stores fat, which is required in moderation for normal body function.
One of Mother Nature's latest gifts to medical science is stirring excitement with the discovery that the substance â€” obtained from a coral-reef inhabiting cyanobacterium â€” appears to be an ideal blueprint for developing new drugs for serious fractures, osteoporosis, and other bone diseases.
A new study provides insight into how stress impacts the brain and may help to explain why some individuals are predisposed to depression when they experience chronic stress.
WALTHAM, Mass., Jan.
- a meat pie that is usually eaten at Christmas in Quebec