Latest Histone deacetylase Stories
WALTHAM, Mass., Sept. 16 /PRNewswire-FirstCall/ -- Repligen Corporation today reported publication of a preclinical study demonstrating that a novel histone deacetylase (HDAC) inhibitor improved disease symptoms in a transgenic animal model of Huntington's disease.
U.S. chemists synthesize promising anti-cancer product WASHINGTON, Aug.
U.S. scientists say they've found a marine compound that inhibits cancer cell growth in lab tests and that might lead to new anti-cancer drugs. University of Florida College of Pharmacy researchers said the patented compound, called largazole, is derived from cyanobacteria that grow on coral reefs.
Researchers at The Children's Hospital of Philadelphia have manipulated cell activity that occurs during the interruption of blood flow to strongly protect heart tissue in animal studies.
ValiRx plc (AIM:VAL, 'ValiRx'), the cancer therapeutics and diagnostics company, has announced promising in vivo results for its lead molecule VAL 101 which uses its gene silencing technology GeneICE(TM) in preclinical xenograph models of pancreatic cancer.
Gloucester Pharmaceuticals has reported positive data from a Phase II trial of romidepsin, a novel, cyclic peptide, pan-HDAC inhibitor under investigation for hematologic malignancies.
Gloucester Pharmaceuticals today announced that positive data from a Phase 2 trial of romidepsin conducted by the U.S. National Cancer Institute (NCI) were presented at the 13th Congress of the European Hematology Association in Copenhagen, Denmark.
An herb used in traditional medicine by many Middle Eastern countries may help in the fight against pancreatic cancer, one of the most difficult cancers to treat. Researchers at the Kimmel Cancer at Jefferson in Philadelphia have found that thymoquinone, an extract of nigella sativa seed oil, blocked pancreatic cancer cell growth and killed the cells by enhancing the process of programmed cell death.
Reshaping of the DNA scaffolding that supports and controls the expression of genes in the brain may play a major role in the alcohol withdrawal symptoms, particularly anxiety, that make it so difficult for alcoholics to stop using alcohol.
SINGAPORE, June 20 /PRNewswire/ -- S*BIO Pte Ltd announced today that it has become Singapore's first biotechnology company to initiate a Phase I clinical trial of a novel anti-cancer compound.
- A member of the swell-mob; a genteelly clad pickpocket. Sometimes mobsman.