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Latest Histone H3 Stories

2010-12-16 14:59:57

The function of histones -- the proteins that enable yards of DNA to be crammed into a single cell -- depends on a number of chemical tags adorning their exterior. This sophisticated chemical syntax for packaging DNA into tight little coils or unraveling it again -- called the "histone code" -- is the latest frontier for researchers bent on understanding how genetics encodes life. But recent research from the University of North Carolina at Chapel Hill has found a number of issues with...

2010-10-12 18:20:04

Test system on Drosophila should provide the key to histone function The genetic inherited material DNA was long viewed as the sole bearer of hereditary information. The function of its packaging proteins, the histones, was believed to be exclusively structural. Additional genetic information can be stored, however, and passed on to subsequent generations through chemical changes in the DNA or histones. Scientists from the Max Planck Institute for Biophysical Chemistry in Göttingen have...

2009-10-22 14:37:51

A study from the University of North Carolina at Chapel Hill has identified a key player in a molecular process essential for DNA replication within cells. The new findings highlight a protein called FLASH, already shown to play a role in initiating apoptosis, or programmed cell death. Apoptosis is a normal biochemical response that occurs when a cell is damaged beyond repair after viral infection or accumulation of mutations that could lead to uncontrolled cellular proliferation, or cancer....

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2009-04-16 15:37:52

An Emory University study shows some of the first direct evidence of a process required for epigenetic reprogramming between generations "“ a finding that could shed more light on the mechanisms of fertilization, stem-cell formation and cloning. The journal Cell published the results of the study on the nematode C. elegans in its April 17 issue. "We believe that we have demonstrated one of the processes that erases the information in a fertilized egg, so that the offspring can begin...

2008-12-05 09:34:57

The Stowers Institute's Workman Lab has discovered a novel histone demethylase protein complex characterized in work published today in Molecular Cell.The Histone H3 protein is an important component of chromatin, the packing material wrapping up chromosomal DNA and preventing unwanted transcription of the message encoded in the DNA. Histone H3 can be altered by adding (methylating) or removing (demethylating) methyl groups from the histone protein. When genes are transcribed, parts of...

2005-08-25 12:16:15

CHAPEL HILL -- Scientists at the University of North Carolina at Chapel Hill have identified a molecular protein's critical role in cell division and growth. The new study, published in the September issue of Nature Structural & Molecular Biology, describes how the protein Upf1 helps cells synchronize the synthesis of both DNA and histones, the group of proteins that organize DNA within a cell's nucleus. The findings may offer new knowledge into the molecular mechanisms involved in...

2005-07-05 09:31:48

NEW YORK (Reuters Health) -- Identical twins are often remarkably similar, yet they have distinct differences. This might seem unexpected since they share all of the same genes, but scientists have come up with an explanation. Small differences in which genes are turned on or off, and to what degree, account for the subtle differences in physical appearance or other characteristics, according to a report in the Proceedings of the National Academy of Sciences. For instance, one twin may be...


Word of the Day
tessitura
  • The prevailing range of a vocal or instrumental part, within which most of the tones lie.
This word is Italian in origin and comes from the Latin 'textura,' web, structure.