Latest Histone Stories
Most cancer treatments are blunt. In an attempt to eradicate tumors, oncologists often turn to radiation or chemotherapy, which can damage healthy tissue along with the cancerous growths.
Double-strand breaks in DNA happen every time a cell divides and replicates.
In a novel use of gene knockout technology, researchers at the University of California, San Diego School of Medicine tested the same gene inserted into 90 different locations in a yeast chromosome – and discovered that while the inserted gene never altered its surrounding chromatin landscape, differences in that immediate landscape measurably affected gene activity.
Researchers have uncovered a new element of the honeybee's genetic makeup, shedding light on why bees are so sensitive to environmental changes.
Changes in how DNA interacts with histones—the proteins that package DNA—regulate many fundamental cell activities from stem cells maturing into a specific body cell type or blood cells becoming leukemic.
Over the last two decades, scientists have come to understand that the genetic code held within DNA represents only part of the blueprint of life.
Two opposing teams battle it out to regulate gene expression on the DNA playing field. One, the activators, keeps DNA open to enzymes that transcribe DNA into RNA.
It's widely accepted that molecular mechanisms mediating epigenetics include DNA methylation and histone modifications, but a team from Thomas Jefferson University has evidence to the contrary regarding the role of histone modifications.
- In medieval musical notation, a sign or neume denoting a shake or trill.