Latest Histopathology Stories
NEW YORK (Reuters Health) - Men undergoing a prostate biopsy may experience less discomfort if they're given a suppository containing the local anesthetic lidocaine a couple of hours before the procedure. While a biopsy when prostate cancer is suspected can be life saving -- or help avoid unnecessary surgery if it proves negative -- the procedure can be uncomfortable or even painful. It involves insertion of an ultrasound probe into the rectum so the prostate can be visualized, and...
By David DouglasNEW YORK -- An olive-oil based herbal extract preparation called Zyflamend suppresses the growth of prostate cancer cells and induces prostate cancer cells to self-destruct, according to a new study.Zyflamend has the ability, in culture at least, to reduce prostate cancer cell growth by as much as 78 percent and induce cancer cell death or "apoptosis," scientists report in the journal Nutrition and Cancer."Together, these results suggest that Zyflamend might...
Using a nuclear magnetic resonance technique, University of Illinois at Chicago chemists have obtained the first molecular-level images of precursors of bundled fibrils that form the brain plaques seen in Alzheimer's disease. Untangling the molecular structure of these pre-fibril forms, which may be the key neurotoxins in Alzheimer's, may help identify targets for new drugs to combat many neurodegenerative diseases. Microscopic bundled fibrils made of proteins called amyloid-beta are presumed...
Bethesda, MD "“ A group of researchers from Mexico has discovered that a diet rich in soy protein may alleviate fatty liver, a disease which often accompanies diabetes. The details of their findings appear in the September issue of the Journal of Lipid Research, an American Society for Biochemistry and Molecular Biology journal. The high levels of insulin and insulin-resistance that accompany diabetes are often associated with fatty liver or hepatic steatosis, an untreatable condition that...
In the July issue of Cell Metabolism, researchers report the discovery of a trigger for insulin resistance in the liver. Hepatic insulin resistance is a silent condition that increases the chances of developing diabetes and heart disease. The team's findings also identify a potential target for drugs to prevent or treat the condition, the researchers said. The livers of mice lacking an enzyme called mitochondrial acyl-CoA:glycerol-sn-3-phosphate acyltransferase 1 (mtGPAT1) remain sensitive to...
An international team of chemists and molecular biologists has discovered a fundamental molecular mechanism that seems to play an important role in Alzheimer's disease, Parkinson's disease, mad cow disease and two-dozen other degenerative and fatal diseases. The discovery is reported June 9 in the journal Nature, where it is featured on the cover. Amyloid fibrils, rope-like structures formed by linked protein molecules, are the common feature of these diseases and may well hold important...
