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Latest Histopathology Stories

2010-04-12 07:34:13

The Atomic Force Microscope depicts on its screen the few nanometer thick and few micrometer long fibers as white flexible sticks, crisscrossing the surface on which they are deposited. The very peculiar property of these proteins lies in fact that they can self assemble into complex ribbon-like twisted fibers. Researchers at ETH Zrich, EPF Lausanne and University of Fribourg have teamed up to take Atomic Force Microscopy images of the fibers and to analyze them using concepts from polymer...

2010-03-08 09:47:00

-- Gene Linked to Eosinophilic Esophagitis Plays Key Role in Inflammation-- PHILADELPHIA, March 8 /PRNewswire-USNewswire/ -- Pediatrics researchers have identified the first major gene location responsible for a severe, often painful type of food allergy called eosinophilic esophagitis (EoE). In this disease, which may cause weight loss, vomiting, heartburn and swallowing difficulties, a patient may be unable to eat a wide variety of foods. After performing a genome-wide association...

2010-03-08 08:23:19

Gene linked to eosinophilic esophagitis plays key role in inflammation Pediatrics researchers have identified the first major gene location responsible for a severe, often painful type of food allergy called eosinophilic esophagitis (EoE). In this disease, which may cause weight loss, vomiting, heartburn and swallowing difficulties, a patient may be unable to eat a wide variety of foods. After performing a genome-wide association study, the study team found EoE was linked to a region of...

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2010-03-03 12:48:56

EPFL's Brain Mind Institute finds clues to the role of brain plaques typical in Alzheimer's patients A study from EPFL's (Ecole Polytechnique F©d©rale de Lausanne) Laboratory of Neuroenergetics and Cellular Dynamics in Lausanne Switzerland, published today in the Journal of Neuroscience, may lead to new forms of treatment following a better understanding of how Amyloid-Beta found in cerebral plaques, typically present in the brain of Alzheimer's patients, may lead to...

2010-02-05 15:02:54

Barrett's epithelium is recognized as a complication of erosive esophagitis and is the pre-malignant condition for adenocarcinoma of the esophagus. A research team from Yokohama City University School of Medicine hypothesized that some macroscopic features of Barrett's epithelium might be useful for identifying a subgroup with a high risk for the development of esophageal adenocarcinoma. Their study will be published on January 28, 2010 in the World Journal of Gastroenterology. They enrolled...

2010-01-14 14:19:50

An article and commentary published online January 13 in the Journal of the National Cancer Institute review available data on diagnosis and management of ductal carcinoma in situ (DCIS), and offer recommendations for the field. These include identification of better risk stratification methods, consideration of the elimination of the word "carcinoma" from the name, and further investigation into whether imaging technology and guidelines can be modified to focus on high-risk lesions. The...

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2009-12-04 09:10:30

A major discovery is challenging accepted thinking about amyloids "“ the fibrous protein deposits associated with diseases such as Alzheimer's and Parkinson's "“ and may open up a potential new area for therapeutics. It was believed that amyloid fibrils - rope-like structures made up of proteins sometimes known as fibers - are inert, but that there may be toxic phases during their formation which can damage cells and cause disease. But in a paper published today [04 December 2009]...

2009-12-03 15:51:59

Scientists at Boston Biomedical Research Institute (BBRI) and the University of Pennsylvania have found that combining two chemicals, one of which is the green tea component EGCG, can prevent and destroy a variety of protein structures known as amyloids. Amyloids are the primary culprits in fatal brain disorders such as Alzheimer's, Huntington's, and Parkinson's diseases. Their study, published in the current issue of Nature Chemical Biology (December 2009), may ultimately contribute to...

2009-12-03 15:35:00

Scientists at Boston Biomedical Research Institute (BBRI) and the University of Pennsylvania have found that combining two chemicals, one of which is the green tea component EGCG, can prevent and destroy a variety of protein structures known as amyloids. Amyloids are the primary culprits in fatal brain disorders such as Alzheimer's, Huntington's, and Parkinson's diseases. Their study, published in the current issue of Nature Chemical Biology (December 2009), may ultimately contribute to...

2009-11-11 18:05:06

Protein reduces levels of amyloid beta and tau hyperphosphorylation, 2 hallmarks of Alzheimer's Investigators at Burnham Institute for Medical Research (Burnham) and colleagues have identified a novel mouse gene (Rps23r1) that reduces the accumulation of two toxic proteins that are major players in Alzheimer's disease: amyloid beta and tau. The amyloid and tau lowering functions of this gene were demonstrated in both human and mouse cells. Amyloid beta is responsible for the plaques found in...


Word of the Day
holluschickie
  • A 'bachelor seal'; a young male seal which is prevented from mating by its herd's older males (mated bulls defending their territory).
This comes from the Russian word for 'bachelors.'
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