Latest Histopathology Stories

(Ivanhoe Newswire) "“ The little-studied amyloid peptide may be promoting Alzheimer's disease (AD), according to this study. Their findings show that the peptide is more abundant, more neurotoxic, and exhibits a higher propensity to aggregate than other agents studied earlier.An irreversible, progressive brain disease affecting millions worldwide, Alzheimer's disease is devastating for its victims, robbing them of their memory and cognitive skills and ultimately of their lives. Even after...

Highly aggregative and neurotoxic amyloid peptide A-beta-43 points the way to new approaches for AD diagnosis and treatmentResearchers at the RIKEN Brain Science Institute (BSI) and their collaborators have shed light on the function of a little-studied amyloid peptide in promoting Alzheimer's disease (AD). Their surprising findings reveal that the peptide is more abundant, more neurotoxic, and exhibits a higher propensity to aggregate than amyloidogenic agents studied in earlier research,...

Highly aggregative and neurotoxic amyloid peptide Abeta43 points the way to new approaches for AD diagnosis and treatmentTokyo, July 4, 2011 - (ACN Newswire) - Researchers at the RIKEN Brain Science Institute (BSI) and their collaborators have shed light on the function of a little-studied amyloid peptide in promoting Alzheimer's disease (AD). Their surprising findings reveal that the peptide is more abundant, more neurotoxic, and exhibits a higher propensity to...

Overexpression of gene is linked with Alzheimer's disease and down syndromeChronic stress has long been linked with neurodegeneration. Scientists at USC now think they may know why.The study, which has tremendous implications for understanding and treating Alzheimer's disease, was published in the June issue of The FASEB Journal (the Journal of the Federation of American Societies for Experimental Biology).Corresponding author Kelvin J. A. Davies, the James E. Birren Chair at the USC Davis...

University of Tennessee molecular biophysics professor reveals a key trigger to a rare but deadly neurodegenerative diseaseJeremy Smith, Governor's Chair for Molecular Biophysics at the University of Tennessee, Knoxville, has helped reveal a key trigger of Gerstmann"“Sträussler"“Scheinker (GSS) syndrome, a rare but deadly neurodegenerative disease. The finding could have far-reaching implications for the treatment of other neurodegenerative diseases such as Alzheimer's, Huntington's,...

-20-month extension of the Gen-Probe license- QUEBEC CITY, June 15, 2011 /PRNewswire/ - DiagnoCure, Inc. (TSX: CUR), a life sciences company commercializing high value cancer diagnostic tests and delivering laboratory services, today reported the issuance of a new U.S. patent, which represents a significant addition to DiagnoCure's PCA3 prostate cancer biomarker portfolio. Moreover, in addition to providing greater patent protection, this new patent bears an extended...

In a large study of men in Japan, the presence of fatty liver disease by ultrasonography showed an inverse ( reduced risk) association with the frequency of moderate alcohol consumption; however, there was some suggestion of an increase in fatty liver disease with higher volume of alcohol consumed per day. Moderate drinkers had lower levels of obesity than did non-drinkers, and both obesity and metabolic abnormalities were positively associated with fatty liver disease.These findings support...

An antioxidant may prevent damage to the liver caused by excessive alcohol, according to new research from the University of Alabama at Birmingham. The findings, published online April 21, 2011, in the journal Hepatology, may point the way to treatments to reverse steatosis, or fatty deposits in the liver that can lead to cirrhosis and cancer.The research team, led by Victor Darley-Usmar, Ph.D., professor of pathology at UAB, introduced an antioxidant called mitochondria-targeted ubiquinone,...

NIH-funded researchers gain ground in treatmentA specific form of vitamin E improved the most severe form of fatty liver disease in some children, according to a study funded by the National Institutes of Health. Results appear in the April 27 issue of the Journal of the American Medical Association. A previous study found vitamin E effective in some adults with the disease.Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease among U.S. children. NAFLD ranges in...

PARIS, April 22, 2011 /PRNewswire/ -- On the occasion of the 46th Congress of the European Association for the Study of the Liver, the VCTE(TM) (Vibration Controlled Transient Elastography) from Echosens stood out as a leading technique in the field. It is the only technique able to measure elasticity at a predetermined, controlled frequency (50 Hz), which is essential because elasticity increases as frequency increases. Today, liver elasticity is recognized as an indicator of...