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Latest HLA-A Stories

2014-07-18 23:04:21

Omixon Holotype HLA is a combination NGS Assay and Software product that provides the most accurate high-resolution, high-throughput HLA genotyping available. Budapest, Hungary & Cambridge, MA (PRWEB) July 18, 2014 Global biotechnology company Omixon, headquartered in Budapest with US offices in Cambridge, MA, announces the launch of Omixon Holotype HLA™ - a combination Assay and Software product that leverages the power of Next Generation Sequencing (NGS), for use on the...

2014-06-04 23:07:57

Omixon and CHOP have used next-generation sequencing tools to significantly advance HLA typing, characterizing whole genes with variations fully phased. Cambridge, MA (PRWEB) June 04, 2014 Global bioinformatics software company Omixon, headquartered in Budapest with US offices in Cambridge, MA, announces an exclusive licensing agreement with The Children’s Hospital of Philadelphia (CHOP) to commercialize a new Next Generation Sequencing (NGS) HLA genotyping assay, for use on the...

2014-06-01 08:20:27

Pre-specified MGMT and HLA Subgroup Analyses Show Potentially Clinically Meaningful Survival Advantages for ICT-107 Treated Patients LOS ANGELES, June 1, 2014 /PRNewswire/ -- ImmunoCellular Therapeutics, Ltd. ("ImmunoCellular") (NYSE MKT:IMUC) announced that updated efficacy and safety data from the phase II trial of dendritic cell-based immunotherapeutic vaccine ICT-107 in patients with newly diagnosed glioblastoma multiforme (GBM) were presented at the 2014 American Society for Clinical...

2012-08-04 02:33:57

Human HLA genes — the genes that allow our immune system to tell the difference between our own cells and foreign invaders — are evolving much more rapidly than previously thought, according to an article online on August 3rd in Trends in Genetics. The resulting degree of variation improves our ability to fight off disease, but could also present challenges to current worldwide efforts aimed at identifying potential donors for patients undergoing stem cell transplantation....

2012-07-19 02:35:57

Animal model replicates human immune response against HIV, could simplify vaccine trials One of the challenges to HIV vaccine development has been the lack of an animal model that accurately reflects the human immune response to the virus and how the virus evolves to evade that response. In the July 18 issue of Science Translational Medicine, researchers from the Ragon Institute of Massachusetts General Hospital (MGH), MIT and Harvard report that a model created by transplanting elements...

2012-05-29 08:12:26

Researchers identify mechanism key in drug allergy Adverse drug reactions are a major issue that cause harm, are costly and restrict treatment options for patients and the development of new drugs. A groundbreaking finding by researchers from the La Jolla Institute for Allergy & Immunology could lead to a new way to dramatically improve drug safety by identifying drugs at risk to cause potentially fatal genetic-linked hypersensitivity reactions before their use in man....

2012-01-10 23:20:43

The cocktail maintaining immune gene variation The great variation of a specific form of immune genes makes organ transplants so complicated. On the other hand, we need such a great variability in order to resist infectious diseases. This is why it also plays a major role in the selection of sexual partners. Up until now, the mechanisms for maintaining this standing genetic variation have remained an evolutionary puzzle. In a study of sticklebacks, researchers from the Max Planck Institute...

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2011-08-26 05:05:08

  Sexual encounters with Neanderthals produced offspring who inherited vital genes that have helped modern humans combat illness and disease, according to a study published Thursday in the journal Science. The scientists extracted material from the leg of a Neanderthal and the fingerbone of a Denisovan, an apparent sister species, which yielded readable DNA.  An analysis of the DNA revealed that most of us have some of the genes of these ancient humans. Indeed, the...

2011-07-11 20:04:33

A study involving over 5,000 people living with the joint disorder ankylosing spondylitis has identified a series of genetic variants associated with increased susceptibility to the condition as well as providing new clues to how the condition may be treated in the future. The study, a collaboration between the Australo-Anglo-American Spondyloarthritis Consortium and the Wellcome Trust Case Control Consortium, also provides one of the first confirmed examples of gene-gene interaction seen in...

2011-01-06 03:36:00

Women who have multiple sclerosis (MS) are more likely to have a gene associated with multiple sclerosis than men with the disease and it is this gene region where environment interacts with the genetics, according to a study published in the January 5, 2011, online issue of Neurology®, the medical journal of the American Academy of Neurology. Research has shown that the number of people diagnosed with MS has been rising, and the rate has been rising faster for women than...


Word of the Day
grass-comber
  • A landsman who is making his first voyage at sea; a novice who enters naval service from rural life.
According to the OED, a grass-comber is also 'a sailor's term for one who has been a farm-labourer.'