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Latest HLA-B Stories

2013-10-22 12:29:36

LONDON, Oct. 22, 2013 /PRNewswire/ -- ViiV Healthcare today announced the submission of a regulatory application in the United States for its investigational single-tablet regimen (STR) combining dolutegravir, abacavir and lamivudine for the treatment of people living with HIV-1. This New Drug Application (NDA) follows the approval of dolutegravir by the US Food and Drug Administration (FDA) in August 2013 under the brand name Tivicay(®), approved for use in combination with other...

Behcet’s Disease Has Genetic Link To Ancient Silk Road Trade Route
2013-01-07 10:42:03

Lawrence LeBlond for redOrbit.com - Your Universe Online Researchers continuing the study of the human genome have mapped out four new regions that are associated with a painful and often dangerous condition–Behcet´s disease–found in people with a lineage to ancestors along the Silk Road. The Silk Road was used as an important trade route for nearly 2,000 years, linking the Far East and Europe. But along with the trade of goods and cultures, also came the exchange of...

2012-07-19 02:35:57

Animal model replicates human immune response against HIV, could simplify vaccine trials One of the challenges to HIV vaccine development has been the lack of an animal model that accurately reflects the human immune response to the virus and how the virus evolves to evade that response. In the July 18 issue of Science Translational Medicine, researchers from the Ragon Institute of Massachusetts General Hospital (MGH), MIT and Harvard report that a model created by transplanting elements...

2012-05-31 23:00:20

"Ankylosing spondylitis is now being treated with regenerative medicine at he center for regenerative medicine." according to A.J. Farshchian MD an orthopedic regenerative practitioner at the center for regenerative medicine. Miami, Florida (PRWEB) May 30, 2012 "Ankylosing spondylitis is now being treated with regenerative medicine at he center for regenerative medicine." according to A.J. Farshchian MD an orthopedic regenerative practitioner at the center for regenerative medicine....

2012-05-29 14:21:11

ST. PAUL, Minn., May 29, 2012 /PRNewswire-iReach/ -- MD Bioproducts launches a new subtype specific antibody as a marker for ankylosing spondylitis (AS): HLA-B*2705. The anti-HLA-B*2705 antibody, clone MARB4, has been validated for use in flow cytometry, tissue staining and immunoprecipitation. (Photo: http://photos.prnewswire.com/prnh/20120529/CG15198) Ankylosing spondylitis (AS) is a chronc inflammatory arthritis. It is characterized by inflammation of the joints between the spinal...

2012-05-29 08:12:26

Researchers identify mechanism key in drug allergy Adverse drug reactions are a major issue that cause harm, are costly and restrict treatment options for patients and the development of new drugs. A groundbreaking finding by researchers from the La Jolla Institute for Allergy & Immunology could lead to a new way to dramatically improve drug safety by identifying drugs at risk to cause potentially fatal genetic-linked hypersensitivity reactions before their use in man....

2012-05-22 23:00:55

Research links abacavir hypersensitivity reactions to attacks by body's own immune system Potentially severe hypersensitivity reactions to the anti-HIV drug abacavir occur through an autoimmune mechanism, resulting from the creation of drug-induced immunogens that are attacked by the body's immune system, according to a study published online by the journal AIDS, official journal of the International AIDS Society. AIDS is published by Lippincott Williams & Wilkins, a part of Wolters...

2011-11-21 07:30:00

VAN NUYS, Calif., Nov. 21, 2011 /PRNewswire/ -- The Spondylitis Association of America (SAA) and leading disease experts from around the world met during the American College of Rheumatology (ACR) Annual Scientific Meeting in Chicago, IL to discuss the latest data and treatment breakthroughs around spondyloarthropathies. ACR is one of the premier congresses highlighting innovative research in the treatment of people with these debilitating diseases, with more than numerous...

science-082611-001
2011-08-26 05:05:08

  Sexual encounters with Neanderthals produced offspring who inherited vital genes that have helped modern humans combat illness and disease, according to a study published Thursday in the journal Science. The scientists extracted material from the leg of a Neanderthal and the fingerbone of a Denisovan, an apparent sister species, which yielded readable DNA.  An analysis of the DNA revealed that most of us have some of the genes of these ancient humans. Indeed, the...

2011-07-11 20:04:33

A study involving over 5,000 people living with the joint disorder ankylosing spondylitis has identified a series of genetic variants associated with increased susceptibility to the condition as well as providing new clues to how the condition may be treated in the future. The study, a collaboration between the Australo-Anglo-American Spondyloarthritis Consortium and the Wellcome Trust Case Control Consortium, also provides one of the first confirmed examples of gene-gene interaction seen in...