Latest HLA-DQ2 Stories
Peer-Reviewed Articles Highlight Advances in Understanding Autoimmune Processes CAMBRIDGE, Mass., April 19, 2013 /PRNewswire/ -- In autoimmune disorders such as celiac disease and Type 1 diabetes, the body's immune system attacks its own cells. Current treatments for many autoimmune disorders are limited to immunosuppressants, but researchers are exploring the possibility of using therapeutic vaccines known as antigen-specific immunotherapy. Currently a vaccine that is designed to...
Connie K. Ho for redOrbit.com – Your Universe Online Observations of the relationship between gluten and T-cells in the immune system have allowed researchers from Monash University to get a better understanding on how celiac disease comes into being. According to the scientists, the disorder impacts a significant part of the population--specifically 1 in 133 people. Due to immune response genes HLA-DQ2 or HLA-DQ8, almost half of the population is susceptible to contracting celiac...
CAMBRIDGE, Mass., Oct. 11, 2012 /PRNewswire/ -- A link between gluten and the immune system has literally been visualized in new research published today in a leading scientific journal, Immunity. The discovery is the collaborative work of research groups in Australia, the Netherlands and ImmusanT Inc. based in Cambridge, Massachusetts, led by Professor Jamie Rossjohn and Dr. Hugh Reid at Monash University, Dr. Bob Anderson of ImmusanT and Professor Frits Koning at the University of...
CHICAGO, May 9, 2011 /PRNewswire/ -- ImmusanT, Inc., a biotechnology company developing an immunotherapeutic vaccine, companion diagnostic and monitoring tool for celiac disease, reported positive results from a Phase 1 study evaluating the safety, tolerability and bioactivity of Nexvax2® in patients with celiac disease. ImmusanT Chief Scientific and Medical Officer Dr. Bob Anderson presented results from the Nexvax2 Phase 1 study and led a symposium and session discussions about celiac...
By Wieser, Herbert Koehler, Peter ABSTRACT Celiac disease (CD) is an inflammatory disorder of the upper small intestine triggered by the ingestion of wheat, rye, barley, and possibly oat products. The clinical feature of CD is characterized by a flat intestinal mucosa with the absence of normal villi, resulting in a generalized malabsorption of nutrients. The prevalence of CD among Caucasians is now thought to be in a range of 1:100-300. There is a strong genetic association with human...
