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Latest Homeobox protein NANOG Stories

2014-07-10 12:34:40

Centro Nacional de Investigaciones Oncologicas (CNIO) The pluripotency factor NANOG regulates cell proliferation in epithelia of the skin and oesophagus in adult organisms; blocking the action of the gene diminishes the capacity of tumour cells to divide Scientists from the Spanish National Cancer Research Centre (CNIO) have discovered that NANOG, an essential gene for embryonic stem cells, also regulates cell division in stratified epithelia—those that form part of the epidermis of...

2014-06-17 10:29:40

Rice University Rice University scientists apply new theory to learn how and why cells differentiate How does a stem cell decide what path to take? In a way, it’s up to the wisdom of the crowd. The DNA in a pluripotent stem cell is bombarded with waves of proteins whose ebb and flow nudge the cell toward becoming blood, bone, skin or organs. A new theory by scientists at Rice University shows the cell’s journey is neither a simple step-by-step process nor all random....

2013-06-18 13:52:00

-A protein called Nanog helps the renewal of healthy embryonic stem cells. -This study shows that Nanog also promotes cancer stem cell proliferation in head and neck cancer and shows how it promotes their growth. -The findings could lead to new, novel treatments for head and neck cancer. A new study led by researchers at The Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC—James) has...

2012-09-27 13:38:03

Researchers at Moffitt Cancer Center have discovered that the micro ribonucleic acid miR-214 plays a critical role in regulating ovarian cancer stem cell properties. This knowledge, said the researchers, could pave the way for a therapeutic target for ovarian cancer. The study appears in a recent issue of the The Journal of Biological Chemistry. According to the study´s lead author, Jin Q. Cheng, Ph.D., M.D., senior member of the Molecular Oncology Department and Molecular Oncology...

2012-05-11 15:09:28

New research findings show that embryonic stem cells unable to fully compact the DNA inside them cannot complete their primary task: differentiation into specific cell types that give rise to the various types of tissues and structures in the body. Researchers from the Georgia Institute of Technology and Emory University found that chromatin compaction is required for proper embryonic stem cell differentiation to occur. Chromatin, which is composed of histone proteins and DNA, packages DNA...

2012-04-05 21:16:03

Yale researchers show in detail how three genes within human embryonic stem cells regulate development, a finding that increases understanding of how to grow these cells for therapeutic purposes. This process, described in the April 6 issue of the journal Cell Stem Cell, is different in humans than in mice, highlighting the importance of research using human embryonic stem cells. "It is difficult to deduce from the mouse how these cells work in humans," said Natalia Ivanova, assistant...

2011-11-04 21:15:55

Inserm's AVENIR "Genomic plasticity and aging" team, directed by Jean-Marc Lemaitre, Inserm researcher at the Functional Genomics Institute (Inserm/CNRS/Université de Montpellier 1 and 2), has recently succeeded in rejuvenating cells from elderly donors (aged over 100). These old cells were reprogrammed in vitro to induced pluripotent stem cells (iPSC) and to rejuvenated and human embryonic stem cells (hESC): cells of all types can again be differentiated after this genuine...

2011-04-28 14:38:17

Like people with a big choice to make, stem cells have a process to "decide" whether to transform into a specific cell type or to stay flexible, a state that biologists call "pluripotency." Using a technology he invented, Brown researcher William Fairbrother and colleagues have discovered new molecular interactions in the process that will help regenerative medicine researchers better understand pluripotency. In a paper published in advance online in the journal Genome Research, Fairbrother's...

2011-03-07 14:24:45

The diagnostic test enables accurate, rapid assessment of the quality of stem cell lines "Pluripotent" stem cells"”which have the potential to mature into almost any cell in the body"”are being widely studied for their role in treating a vast array of human diseases and for generating cells and tissues for transplantation. Now, a team of Scripps Research Institute scientists has created a quality control diagnostic test that will make it much easier for researchers to determine...

2011-02-01 16:59:00

MIAMI, Feb. 1, 2011 /PRNewswire-USNewswire/ -- During a ceremony at NANOG51 in Miami, Steve Feldman of NewNOG Inc. and Donald Welch of Merit Network Inc. signed an agreement to transfer ownership of the North American Network Operators' Group (NANOG) trademark, meeting archives, and domain (nanog.org) to NewNOG. The agreement comes after months of discussions between NewNOG, Merit Network, and University of Michigan. "Today is a milestone in the history of NANOG," Feldman said during the...


Word of the Day
pungle
  • To take pains; labor assiduously with little progress.
This word comes from the Spanish 'pongale,' put it.
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