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Latest Homeobox protein NANOG Stories

2009-03-19 09:35:50

Burnham Scientists Identify Protein that Controls Differentiation in Human and Mouse Embryonic Stem CellsInvestigators at Burnham Institute for Medical Research (Burnham) have learned that a protein called Shp2 plays a critical role in the pathways that control decisions for differentiation or self-renewal in both human embryonic stem cells (hESCs) and mouse embryonic stem cells (mESCs).The research, led by Gen-Sheng Feng, Ph.D., differs with some earlier findings that suggested hESCs and...

2009-01-06 11:37:31

Scientists at the Stanford University School of Medicine and at UC-San Francisco have succeeded in isolating stem cells from human testes. The cells bear a striking resemblance to embryonic stem cells "” they can differentiate into each of the three main types of tissues of the body "” but the researchers caution against viewing them as one and the same.According to the study, the testes stem cells have different patterns of gene expression and regulation and they do not...

2008-11-14 09:00:34

CAMBRIDGE, England, November 14 /PRNewswire-FirstCall/ -- - European IRES Patent Upheld and UK Patent on Cell Screening Technology Granted - ("Stem Cell Sciences", "SCS", "the Company") IRES Patent Upheld in Appeal Hearing at the EPO Stem Cell Sciences plc (AIM:STEM, ASX:STC) announces that European patent no. 0695361 covering its IRES technology was upheld by the European Patent Office in Munich on 12th November 2008. The EPO Technical Board of Appeal dismissed objections against...

2008-09-19 15:00:25

A team of scientists at IBM (NYSE: IBM) and the Genome Institute of Singapore (GIS) have discovered that microRNAs --small molecules that are an important regulatory component in the machinery of living cells -- actually regulate the differentiation of stem cells and have roles that go way beyond what was previously thought. The work uncovers new ways by which microRNAs regulate how genes are made and could provide alternative explanations for some observations that biologists have made in...

2008-08-13 15:01:02

U.S. scientists say they've discovered how microRNA molecules are activated -- an event that is critical for the creation of embryonic stem cells. MicroRNAs, along with proteins called master transcription factors, instruct embryonic stem cells to either reproduce or begin their transformation into another cell type, such as a skin or muscle cell, the researchers said. Prior studies showed the importance of microRNAs in the maintenance of embryonic stem cells in their embryonic state, but...

2008-07-16 15:01:08

Reportlinker.com announces that a new market research report related to the Medical devices industry is available in its catalogue. Stem Cell Markets http://www.reportlinker.com/p090979/Stem-Cell-Markets.html A stem cell is an extraordinary type of cell that has the ability to self-renew for long periods of time and to differentiate into specialized cells under appropriate physiological or experimental conditions. Traditionally, stem cells have been classified as either embryonic, adult...

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2008-03-24 11:05:00

M. D. Anderson team connects REST to regenerative medicine, pediatric brain cancerA protein known as REST blocks the expression of a microRNA that prevents embryonic stem cells from reproducing themselves and causes them to differentiate into specific cell types, scientists at The University of Texas M. D. Anderson Cancer Center report in the journal Nature. Researchers show RE1-silencing transcription factor (REST) plays a dual role in embryonic stem cells, said senior author Sadhan...

2006-06-14 12:04:21

By Patricia Reaney LONDON (Reuters) - A gene named after the mythical Celtic land of the ever young could help explain how to reprogram adult cells into embryonic stem cells to treat diseases, researchers said on Wednesday. They discovered that the gene called Nanog helped to transform adult mouse cells into embryonic stem cells after cell fusion -- when two cells are combined to form a hybrid. "The effect of Nanog is remarkable. All the hybrid cells became fully converted to...

2006-06-14 12:00:00

By Patricia Reaney LONDON -- A gene named after the mythical Celtic land of the ever young could help explain how to reprogram adult cells into embryonic stem cells to treat diseases, researchers said on Wednesday. They discovered that the gene called Nanog helped to transform adult mouse cells into embryonic stem cells after cell fusion -- when two cells are combined to form a hybrid. "The effect of Nanog is remarkable. All the hybrid cells became fully converted to embryonic stem cells,"...

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2005-09-08 14:50:00

What exactly makes a stem cell a stem cell? The question may seem simplistic, but while we know a great deal of what stem cells can do, we don't yet understand the molecular processes that afford them such unique attributes. Now, researchers at Whitehead Institute for Biomedical Research working with human embryonic stem cells have uncovered the process responsible for the single-most tantalizing characteristic of these cells: their ability to become just about any type of cell in the body,...