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Last updated on April 24, 2014 at 21:24 EDT

Latest Hormone receptor positive tumor Stories

2011-03-31 01:34:12

The estrogen inhibitor tamoxifen can prevent breast cancer from coming back in treated women whose tumors grow in the presence of the hormone. Unfortunately, tamoxifen's anti-tumor effect wanes in about half of these women, and now researchers from the Lester and Sue Smith Breast Center at Baylor College of Medicine think they know why. Low levels or loss of the protein Rho guanine disassociation inhibitor alpha or Rho GDI alpha can cause tumors to resist the effects of treatment with...

2009-08-10 11:17:08

The sex hormone estrogen plays a critical role in the regulation of growth and the development of cells. It is also crucial for cell-type-specific gene expression in various tissues. Deregulation of this system results in breast and ovarian cancer. Those tumors are successfully treated with drugs such as tamoxifen. Researchers suggest that this drug inhibits tumor growth by blocking the estrogen receptors of the tumor cells. However, up to now it has been unclear what effect this...