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Last updated on April 18, 2014 at 5:30 EDT

Latest Hospital Medical Center Stories

2014-02-10 11:13:59

Analyzing the genomes of twin 3-year-old sisters – one healthy and one with aggressive leukemia – led an international team of researchers to identify a novel molecular target that could become a way to treat recurring and deadly malignancies. Scientists in China and the United States report their findings online Feb. 9 in Nature Genetics. The study points to a molecular pathway involving a gene called SETD2, which can mutate in blood cells during a critical step as DNA is being...

2014-01-30 10:09:55

Researchers have developed a tool that allows caregivers to quickly and accurately predict the risk of death in children with septic shock – a systemic infection that damages vital organs and one of the leading causes of death among hospitalized children. Reporting their results Jan. 29 in PLOS ONE (published by the Public Library of Science), researchers say the study validates a tool that would let doctors decide much faster which severely sick children need to receive aggressive...

2014-01-27 13:33:18

Researchers at Cincinnati Children's Hospital Medical Center have successfully carried out what is believed to be the first initiative conducted exclusively among teenagers to show significant improvement in their asthma outcomes. The quality improvement initiative, conducted in a primary care setting, dramatically improved asthma control and outcomes for high-risk adolescents. The study is published online in the journal Pediatrics. "Improving asthma is particularly difficult for...

2014-01-20 12:29:27

A new study shows that exposure to secondhand smoke at home or in the car dramatically increases the odds of children being readmitted to the hospital within a year of being admitted for asthma. The study, published in the journal Pediatrics, raises the possibility that measurement of tobacco exposure could be used in clinical practice to target smoking cessation efforts and reduce the likelihood of future hospitalizations. To determine tobacco exposure, the researchers at Cincinnati...

2013-11-21 12:34:44

Researchers at Cincinnati Children's Hospital Medical Center have developed the first molecular test to diagnose eosinophilic esophagitis (EoE), a chronic upper gastrointestinal disorder. The incidence of EoE has skyrocketed since it was first characterized two decades ago. The test, based on a 96 gene expression profile, "offers an unprecedented opportunity to improve diagnosis and treatment, and a platform approach for other inflammatory diseases," says Marc Rothenberg, MD, PhD, director...

2013-10-21 13:27:21

Scientists report in Nature they have found a novel and unexpected molecular switch that could become a key to slowing some of the ravages of getting older as it prompts blood stem cells to age. The study is expected to help in the search for therapeutic strategies to slow or reverse the aging process, and possibly rejuvenate these critically important stem cells (called hematopoietic stem cells, or HSCs), said scientists from Cincinnati Children's Hospital Medical Center and the...

Norovirus Vaccine Trial Shows Promising Results
2013-10-05 05:27:14

redOrbit Staff & Wire Reports - Your Universe Online An experimental norovirus vaccine has been found to reduce the main symptoms of the gastrointestinal infection by more than half, according to research presented this week at the IDWeek 2013 infectious diseases conference in San Francisco. The investigational vaccine, which reportedly appears to be generally well tolerated and effective against the most common strain of the RNA virus, has been found to reduce vomiting and/or...

2013-09-30 12:49:50

Researchers report a skyrocketing increase in the number of visits to the emergency department for kids with sports-related traumatic brain injuries (TBI), such as concussions. The study, conducted by emergency physicians at Cincinnati Children's Hospital Medical Center, shows that emergency visits for sports-related TBI increased 92 percent between 2002 and 2011. The number of children and teens admitted to the hospital with the same diagnosis also increased. That increase was...

2013-09-24 11:00:52

A new study shows that exposure to diesel exhaust particles from traffic pollution leads to increased asthma severity in children. Moreover, the study finds that this is due to increased blood levels of IL-17A, a protein associated with several chronic inflammatory diseases, in children with high diesel exposure. The study by researchers at Cincinnati Children's Hospital Medical Center is published online in the Journal of Allergy and Clinical Immunology. The research, conducted in mice...

2013-09-12 11:34:04

A team of researchers at Cincinnati Children's Hospital Medical Center has developed an antibody that could prevent Candida infections that often afflict hospitalized patients who receive central lines. Margaret Hostetter, MD, director of infectious diseases at Cincinnati Children's, and her team developed the antibody, which prevents Candida albicans from binding to heparin, thereby stopping the formation of biofilm in a rat model of catheter-associated infection. A biofilm is a...