Latest Human Genome Sequencing Center Stories
The completion of three pilot projects designed to determine how best to build an extremely detailed map of human genetic variation begins a new chapter in the international project called 1,000 Genomes, said the director of the Baylor College of Medicine Human Genome Sequencing Center, which is a major contributor to the effort."Mapping all the shared normal variation in human populations is a critical step to interpreting medically actionable genetic changes," said Dr. Richard...
Diversity of human microbes greater than previously predictedThe Human Microbiome Project (HMP) on Thursday published an analysis of 178 genomes from microbes that live in or on the human body. The researchers discovered novel genes and proteins that serve functions in human health and disease, adding a new level of understanding to what is known about the complexity and diversity of these organisms.The human microbiome consists of all the microorganisms that reside in or on the human body....
A pair of University of Houston researchers contributed to the assembly of the first comprehensive DNA sequence of an amphibian genome, which will shed light on the study of embryonic development, with implications for preventing birth defects and more effectively treating many human diseases.Amy Sater and Dan Wells, both professors in UH's department of biology and biochemistry, collaborated with a number of other scientists in what Sater calls "a massive and international effort,"...
Baylor College of Medicine's Dr. James Lupski came to the end of a personal quest earlier this year when the Baylor Human Genome Sequencing Center (www.hgsc.bcm.tmc.edu/) sequenced his complete genome and identified the gene involved in his own form of Charcot-Marie-Tooth syndrome, which affects the function of nerves in the body's limbs, hands and feet. At the same time, the finding opened a new door showing that genome information has clinical importance."This is the first time we have...
Analyzing the genomic structure of five men descended from the hunter-gatherers of southern Africa "“ including famed South African Bishop Desmond Tutu "“ reveals surprising ways in which the genetic codes of these groups differ from others in the world and from each other, said a consortium of experts including those from Baylor College of Medicine in a report that appears today in the journal Nature.In the report, the group describes the fully sequenced genomes of an individual...
Benefits for human health expectedHuman genomes from Southern African Bushmen and Bantu individuals have been sequenced by a team of scientists seeking a greater understanding of human genetic variation and its effect on human health. The study's findings will be published in the journal Nature on 18 February 2010. The research was completed by scientists from American, African, and Australian research institutions, with support from Penn State University in the United States and from several...
The National Institutes of Health (www.nih.gov) today announced expanded funding for Baylor College of Medicine's (www.bcm.edu) Human Genome Sequencing Center for its involvement in the Human Microbiome Project, which seeks to understand how the trillions of microscopic organisms that live in or on the human body affect human health and lives.Also announced was that BCM's Dr. James Versalovic (http://www.bcm.edu/cmb/?pmid=2446) will lead one of 15 pilot clinical demonstration projects.The...
Scientists from the University of Maryland have published a new version of the genome of the domestic cow, known as Bos Taurus, which considerably improves previous assemblies in terms of accuracy and totality.The new cattle sequence took six years to complete, annotate and analyze and has involved over 300 scientists from 25 countries.Sequencing of the bovine genome provides new information about mammalian evolution as well as cattle-specific biology, and points the way to research that...
MOUNTAIN VIEW, Calif., Jan. 30 /PRNewswire/ -- Complete Genomics Inc., a newly launched, third-generation human genome sequencing company, today announced that it will release its sequencing data publically for the first time at the 10th annual Advances in Genome Biology and Technology (AGBT) meeting to be held in Marco Island, Fla., from Feb. 4-7. Dr. Clifford Reid, chairman, president and CEO of Complete Genomics, will review the analysis results during his presentation titled:...
A newly published genome sequence of a breast cancer cell line reveals a heavily rearranged genetic blueprint involving breaks and fusions of genes and a broken DNA repair machinery, said researchers at Baylor College of Medicine in a report that appears online in the journal Genome Research."It's like a computer program that has become buggy and transcends into something dangerous," said Dr. Aleksandar Milosavljevic, associate professor in the BCM Human Genome Sequencing Center. "It...
