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Latest Human leukocyte antigen Stories

2010-11-23 12:55:03

Heavy smokers and individuals with genetic risk factor for RA at greatest risk A new study determined that African Americans who smoke cigarettes have a higher risk of developing rheumatoid arthritis (RA). RA risk is more pronounced among individuals positive for the HLA-DRB1 shared epitope, a genetic risk factor for RA. Findings from this study"”the largest to date examining the impact of smoking on RA risk in an African American population"”are available in the December issue of...

2010-11-18 17:21:06

Suggests new therapies to prevent chronic rejection, stop cancer progression UCLA researchers have pinpointed the culprit behind chronic rejection of heart, lung and kidney transplants. Published in the Nov. 23 edition of Science Signaling, their findings suggest new therapeutic approaches for preventing transplant rejection and sabotaging cancer growth. The team focused on the mechanism behind narrowing of the donor's grafted blood vessels, which blocks blood from reaching the transplanted...

2010-11-01 15:12:07

New approach could speed better tests for earliest appearance of cancer cells and help develop vaccines Scientists at Johns Hopkins have taken a less-is-more approach to designing effective drug treatments that are precisely tailored to disease-causing pathogens, such as viruses and bacteria, and cancer cells, any of which can trigger the body's immune system defenses. In a report to be published in the latest issue of Nature Medicine online Oct. 31, researchers describe a new...

2010-08-16 14:27:42

A team of researchers has discovered new evidence that Parkinson's disease may have an infectious or autoimmune origin. "Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease" appears online in Nature Genetics. The study was conducted by the NeuroGenetics Research Consortium, an international team of researchers led by Haydeh Payami, research scientist at the New York State Department of Health Wadsworth Center. The clinical directors for the...

2010-07-13 15:19:48

Researchers with the National Institutes of Health have found susceptibility to Behcet's disease, a painful, inflammatory condition, to be associated with genes involved in the body's immune response. Although the Greek physician Hippocrates described Behcet's disease (pronounced BET'-chet's), more than 2,000 years ago, the condition existed in relative obscurity until the early 20th century. Named for the Turkish physician who first classified it in 1937, Behcet's disease is found almost...

2010-06-18 01:53:51

Defined sets of factors can reprogram human cells to induced pluripotent stem (iPS) cells. However, many types of human cells are not easily accessible to minimally invasive procedures. In a paper published in the International and American Associations for Dental Research's Journal of Dental Research, lead researcher K. Tezuka and researchers N. Tamaoki, H. Aoki, T. Takeda-Kawaguchi, K. Iida, T. Kunisada and T. Shibata all from the Gifu University Graduate School of Medicine, Japan; and K....

2010-06-17 01:00:00

GERMANTOWN, Md. and HILDEN, Germany, June 17 /PRNewswire-FirstCall/ -- QIAGEN (Nasdaq: QGEN; Frankfurt, Prime Standard: QIA) today announced that it has entered into an agreement with the Dutch molecular diagnostic component supplier Genome Diagnostics which covers the development and commercialization of 6 new tests until 2011. QIAGEN believes that this collaboration will further expand the Company's testing portfolio for the early detection of diseases and individualized treatment of...

2010-05-31 13:06:10

Genome Institute of Singapore and Sun Yat-Sen University Cancer Centre identify 3 new susceptibility genes in genome-wide association study of nasopharyngeal carcinoma Scientists from Singapore, China and USA have identified three new susceptibility genes in a genome-wide association study of nasopharyngeal carcinoma (NPC). The study, led by the Genome Institute of Singapore (GIS), a biomedical research institute of the Agency for Science, Technology and Research (A*STAR), and the Sun Yat-Sen...

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2010-05-06 09:10:00

A new finding from the Ragon Institute of MGH, MIT and Harvard may have implications for designing an effective AIDS vaccine. When people become infected by HIV, it's usually only a matter of time, barring drug intervention, until they develop full-blown AIDS. However, a small number of people exposed to the virus progress very slowly to AIDS "” and some never develop the disease at all. In the late 1990s, researchers showed that a very high percentage of those naturally HIV-immune...

2010-04-20 08:30:00

ADDISON, Texas, April 20 /PRNewswire/ -- New guidelines to diagnose and treat antibody mediated rejection (AMR) in cardiac transplant patients will be the focus of a consensus conference today at the Hilton Chicago. Sponsored jointly by the International Society for Heart and Lung Transplantation (ISHLT) and the California Heart Center Foundation, the conference brings together 75 of the world's leading heart transplant experts to discuss and recommend appropriate treatment protocols....


Word of the Day
caparison
  • A cloth or covering, more or less ornamented, laid over the saddle or furniture of a horse, especially of a sumpter-horse or horse of state.
  • Clothing, especially sumptuous clothing; equipment; outfit.
  • To cover with a caparison, as a horse.
  • To dress sumptuously; adorn with rich dress.
This word ultimately comes from the Medieval Latin 'cappa,' cloak.
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