Quantcast

Latest Human mitochondrial genetics Stories

2011-12-01 18:41:05

Off-patent generic drug Metformin prevents cancer cells from using their mitochondria to grow and spread throughout the body Researchers at the Kimmel Cancer Center at Jefferson have identified cancer cell mitochondria as the unsuspecting powerhouse and "Achilles' heel" of tumor growth, opening up the door for new therapeutic targets in breast cancer and other tumor types. Reporting in the online Dec.1 issue of Cell Cycle, Michael P. Lisanti, M.D., Ph.D., Professor and Chair of Stem...

2011-11-01 21:05:25

Researchers report they have figured out how the cancer-causing bacterium Helicobacter pylori attacks a cell's energy infrastructure, sparking a series of events in the cell that ultimately lead it to self-destruct. H. pylori are the only bacteria known to survive in the human stomach. Infection with H. pylori is associated with an increased risk of gastric cancer, the second-leading cause of cancer-related deaths worldwide. "More than half the world's population is currently infected...

2011-07-28 17:46:56

Max Planck researchers encounter genetic changes in the genome of the cellular power plants of human induced pluripotent stem cells Induced pluripotent stem cells (iPS cells) are truly talented multi-taskers. They can reproduce almost all cell types and thus offer great hope in the fight against diseases like Alzheimer's and Parkinson's. However, it would appear that their use is not entirely without risk: during the reprogramming of body cells into iPS cells, disease-causing mutations can...

2011-06-16 09:42:00

OMAHA, Neb., June 16, 2011 /PRNewswire/ -- Transgenomic, Inc. (OTC/BB: TBIO) today announced the launch of the Nuclear Mitome Test, a genetic test to aid physicians in the diagnosis of mitochondrial disorders. The Nuclear Mitome Test, employs next-generation sequencing technology to identify mutations in more than 400 genes, and represents the most comprehensive genetic test available for mitochondrial disorders. The announcement was made at the 2011 United Mitochondrial Disease Foundation...

2011-06-07 23:01:00

MOUNTAIN VIEW, Calif., June 8, 2011 /PRNewswire/ -- Edison Pharmaceuticals, Inc. announced today the United States Food and Drug Administration has granted orphan drug designation to EPI-743 for treatment of inherited mitochondrial respiratory chain diseases. Today, these mitochondrial diseases affect an estimated 60,000 individuals. The Orphan Drug Act, passed in 1982, provides incentives for companies to pursue treatments for diseases affecting fewer than 200,000 individuals in the...

2011-05-31 13:03:21

Pre-implantation genetic diagnosis (PGD) can give women at risk of passing on a mitochondrial DNA disorder to their offspring a good chance of being able to give birth to an unaffected child, a researcher told the annual conference of the European Society of Human Genetics today (Monday). Dr. Debby Hellebrekers, from Maastricht University Medical Centre, Maastricht, The Netherlands, said that the scientists' findings could have a considerable effect on preventing the transmission of...

2011-05-19 10:26:00

--Children's Hospital of Philadelphia Study May Point to Much-Needed Drug Therapy for Elusive Metabolic Disorders -- PHILADELPHIA, May 19, 2011 /PRNewswire-USNewswire/ -- A human drug that both prevents and cures kidney failure in mice sheds light on disabling human mitochondrial disorders, and may represent a potential treatment in people with such illnesses. "There are no effective cures for mitochondrial diseases, even in animals," said study leader Marni J. Falk, M.D., who cares for...

2011-05-11 00:47:58

Mitochondria are the body's energy producers, the power stations inside our cells. Researchers at the University of Gothenburg, Sweden, have now identified a group of mitochondrial proteins, the absence of which allows other protein groups to stabilise the genome. This could delay the onset of age-related diseases and increase lifespan. Some theories of human ageing suggest that the power generators of the cell, the mitochondria, play a part in the process. In addition to supplying us with...

2011-01-06 16:57:04

Medical researchers who crave a means of exploring the genetic culprits behind a host of neuromuscular disorders may have just had their wish granted by a team working at the National Institute of Standards and Technology (NIST), where scientists have performed surgery on single cells to extract and examine their mitochondria. The scientists reached into these cells and extracted their "engines""”the mitochondria that are in large part responsible for our metabolism. Many human cells...

2010-10-28 12:38:00

--Studying the Cells' Power Plants, a Major Factor in Life Functions-- PHILADELPHIA, Oct. 28 /PRNewswire-USNewswire/ -- Douglas C. Wallace, Ph.D., a pioneer and internationally prominent scientist in the field of human mitochondrial genetics, has joined The Children's Hospital of Philadelphia to continue his investigations into the role of mitochondrial energy in health and disease. In establishing the Center of Mitochondrial and Epigenomic Medicine (CMEM) at Children's Hospital, Wallace...


Word of the Day
lambent
  • Licking.
  • Hence Running along or over a surface, as if in the act of licking; flowing over or along; lapping or bathing; softly bright; gleaming.
This word comes the Latin 'lambere,' to lick.
Related