Latest Huntingtin Stories
-- CHOP Gene Therapy Expert Fine-Tunes Protein Signals, Improves Motor Function and Reduces Brain Shrinkage in a Neurological Disorder -- PHILADELPHIA, Jan.
Novel ZFP Therapeutic Approach Selectively Represses Expression of Huntington's Disease-Causing Gene Variant in Patient-Derived Cells and Animal Models RICHMOND, Calif., Nov.
Researchers believe they have learned how mutations in the gene that causes Huntington’s disease kill brain cells, a finding that could open new opportunities for treating the fatal disorder.
The gene mutation that causes Huntington's disease appears in every cell in the body, yet kills only two types of brain cells. Why? UCLA scientists used a unique approach to switch the gene off in individual brain regions and zero in on those that play a role in causing the disease in mice.
Tweaking a specific cell type's ability to absorb potassium in the brain improved walking and prolonged survival in a mouse model of Huntington's disease.
Working with genetically engineered mice, Johns Hopkins neuroscientists report they have identified what they believe is the cause of the vast disintegration of a part of the brain called the corpus striatum in rodents and people with Huntington's disease: loss of the ability to make the amino acid cysteine.
CARDIFF, Calif., March 4, 2014 /PRNewswire/ -- NI Research has released the March issue of NeuroPerspective,
Proteins are the workhorses of the cell, and their correctly folded three-dimensional structures are critical to cellular functions.
A new study published 26th November in the open access journal PLOS Biology, identifies a new target in the search for therapeutic interventions for Huntington's disease – a devastating late-onset neurodegenerative disorder.
- One who brings meat to the table; hence, in some countries, the official title of the grand master or steward of the king's or a nobleman's household.