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Latest Huntingtin Stories

2011-01-18 19:09:02

This molecule, a tiny strand of nucleotides called microRNA-29 or miR-29, has already been shown to be in short supply in certain neurodegenerative illnesses such as Alzheimer's disease and Huntington's disease. Thus, the discovery could herald a new treatment to prompt brain cells to survive in the wake of neurodegeneration or acute injury like stroke. Researchers at the University of North Carolina at Chapel Hill have discovered a molecule that can make brain cells resistant to programmed...

2011-01-05 22:59:55

Lou Gehrig's disease, or amyotrophic lateral sclerosis (ALS), and frontotemporal lobar degeneration (FTLD) are characterized by protein clumps in brain and spinal-cord cells that include an RNA-binding protein called TDP-43. This protein is the major building block of the lesions formed by these clumps. In a study published in the Journal of Clinical Investigation, a team led by Virginia M.-Y. Lee, PhD, director of Penn's Center for Neurodegenerative Disease Research, describes the first...

2010-12-14 20:21:40

Research presented at American Society for Cell Biology's 50th annual meeting Over expressing a transcription factor that promotes the increase in number of mitochondria greatly improves the neurological function of transgenic mice models for Huntington's disease (HD), researchers today told the American Society of Cell Biology's 50th Annual Meeting in Philadelphia. Albert La Spada, M.D., Ph.D., and colleagues at the UC San Diego (UCSD) explained that over expression of the transcription...

2010-12-08 21:53:01

A new study uncovers a mechanism linking a specific type of cellular stress with brain damage similar to that associated with neurodegenerative disease. A new study uncovers a mechanism linking a specific type of cellular stress with brain damage similar to that associated with neurodegenerative disease. The research, published by Cell Press in the December 9 issue of the journal Neuron, is the first to highlight the significance of the reduction of a specific calcium signal that is directly...

2010-11-15 21:24:38

Fisetin, a naturally occurring compound found in strawberries and other fruits and vegetables, slows the onset of motor problems and delays death in three models of Huntington's disease, according to researchers at the Salk Institute for Biological Studies. The study, published in the online edition of Human Molecular Genetics, sets the stage for further investigations into fisetin's neuroprotective properties in Huntington's and other neurodegenerative conditions. Huntington's disease (HD)...

2010-07-28 14:47:31

Australian scientists have identified the behaviour of the mutant protein "Ëœhuntingtin' which leads to the fatal Huntington's disease providing potential targets to treat the disease, a University of Melbourne study reveals. Huntington's disease is a genetic disease with no cure, characterized by a steady decline in motor control and the dysfunction and death of brain cells. The cause of the disease has long baffled scientists. Symptoms tend to first appear when the person is in...

2010-06-25 13:22:29

Animal models offer clues to similar neurodegenerative disorders in humans, such as Parkinson's A team of researchers, led by scientists at the University of California, San Diego, have identified a key player in the dramatic loss of neurons in mice and fly models, a discovery that could help illuminate the role of mitochondrial dysfunction in human neurodegenerative disorders, such as Parkinson's disease. Writing in the June 24 issue of Neuron, principal investigator Albert La Spada, MD,...

2010-04-20 08:42:55

Stanford University School of Medicine researchers have identified several small molecules that mimic a key but cumbersome protein in the brain, a discovery that could open the door to new therapies for a variety of brain disorders. The protein, designated by the acronym BDNF, is known to be involved in important brain functions that include memory and learning. "These small molecules could be the basis of drugs that provide entirely new avenues of treatment for a large number of...

2010-04-12 07:20:00

Findings by Einstein researchers suggest treatment strategies In a step towards a possible treatment for Huntington's disease, scientists at Albert Einstein College of Medicine of Yeshiva University have shown for the first time that the accumulation of a mutated protein may explain damaging cellular behavior in Huntington's disease. Their research is described in the April 11 online edition of Nature Neuroscience. Huntington's disease, which afflicted the folksinger Woody Guthrie, is a...

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2010-03-24 08:21:37

Animal study furthers our understanding of inherited neurodegenerative disease New research shows how a mutation causes a common inherited neurodegenerative disease, according to a study in the March 24 issue of The Journal of Neuroscience. The study shows that the mutation of a specific protein known to cause Charcot-Marie-Tooth (CMT) disrupts the movement of mitochondria, the energy-supplying machines inside each cell. The regulated movement of mitochondria along nerve cell fibers is vital...


Word of the Day
cenobite
  • One of a religious order living in a convent or in community; a monk: opposed to anchoret or hermit (one who lives in solitude).
  • A social bee.
This word comes from the Latin 'coenobium,' convent, which comes from the Greek 'koinobios,' living in community.
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