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Latest Hydroxyurea Stories

2011-12-12 16:11:38

Young infants and toddlers with sickle cell anemia who received the drug hydroxyurea were no more likely to have cellular genetic damage than those who received a placebo or inactive medicine, said researchers from Baylor College of Medicine in Houston and St. Jude Children's Research Hospital in Memphis, Tenn., yesterday at the American Society of Hematology's annual meeting in San Diego, Calif. These findings provide further evidence of the safety of hydroxyurea for children with sickle...

2011-12-12 15:41:19

Research assessing the safety and efficacy of hydroxyurea therapy in pediatric patients with sickle cell disease (SCD) and the use of pre-operative transfusions for patients with SCD who undergo low- and moderate-risk elective surgery will be presented today at the 53rd Annual Meeting of the American Society of Hematology. An estimated 90,000 to 100,000 Americans are affected each year by SCD, a serious disorder that causes normal red blood cells to become rigid and form in a crescent...

2011-11-02 09:09:31

Laboratory study at University of Michigan Health System shows increasing TR2/TR4 expression can lead to higher fetal hemoglobin levels in sickle cell patients A University of Michigan Health System laboratory study reveals a key trigger for producing normal red blood cells that could lead to a new treatment for those with sickle cell disease. The study, conducted in mice, appears in this week's early edition of the Proceedings of the National Academy of Sciences, and holds promise for...

2011-09-22 11:08:42

More public awareness and education about sickle cell disease, an inherited disease that affects the blood system, is critically important, said a renowned hematologist from Baylor College of Medicine and Texas Children's Hospital. Dr. Russell E. Ware, professor of pediatrics at BCM, director of the Texas Children's Center for Global Health and director of the Texas Children's Hematology Center, offered information on the disease, what causes it, how it is treated and living with sickle...

2011-09-22 11:04:30

As researchers continue to study the use of hydroxyurea as a treatment for sickle cell disease, there is more evidence to validate that it is safe and effective for children with the disease, said an expert pediatric hematologist from Baylor College of Medicine. "We've known about this treatment since the 1960s," said Dr. Russell E. Ware, professor of pediatrics at BCM, director of the Texas Children's Center for Global Health and director of the Texas Children's Hematology Center. "It was...

2011-07-18 14:34:27

A thalidomide analog is shaping up as a safe, worthy opponent of sickle cell disease, Georgia Health Sciences University researchers report. Much like hydroxyurea, the only Food and Drug Administration-approved therapy for sickle cell, pomalidomide increases production of fetal hemoglobin which, unlike its adult counterpart, cannot take on the destructive sickle shape. In stark contrast, pomalidomide also preserves bone marrow function actually increasing proliferation of the cells that make...

2011-05-13 10:43:14

A cancer drug already used to treat adults and school-age children with sickle cell anemia is safe and significantly reduces pain and other complications of the disease in children as young as 9 months, according to a national study involving a UT Southwestern Medical Center researcher. Pediatric researchers at UT Southwestern and 13 other academic medical centers say hydroxyurea should be offered to all young children with sickle cell anemia, regardless of disease severity and clinical...


Word of the Day
omphalos
  • The navel or umbilicus.
  • In Greek archaeology: A central boss, as on a shield, a bowl, etc.
  • A sacred stone in the temple of Apollo at Delphi, believed by the Greeks to mark the 'navel' or exact center-point of the earth.
'Omphalos' comes from the ancient Greek.
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