Quantcast

Latest hyperinsulinism Stories

2014-03-13 17:11:30

A rare and potentially lethal disease of newborn babies whose bodies make too much insulin may be treatable with fish oils, according to researchers from The University of Manchester. The disease, called congenital hyperinsulinism, means that the infant's brain is starved of blood sugar which can lead to brain damage or long-term disability. But by giving the children purified fish oils similar to those used to treat some heart attack patients, alongside standard medical treatment, their...

2011-03-16 13:41:41

University of Manchester scientists have led an international team to discover new treatments for a rare and potentially lethal childhood disease that is the clinical opposite of diabetes mellitus. Congenital hyperinsulinism (CHI) is a condition where the body's pancreas produces too much insulin "“ rather than too little as in diabetes "“ so understanding the disease has led to breakthroughs in diabetes treatment. This latest study, published in the journal Diabetes today...

2011-01-04 13:30:32

The research group led by professor Makoto Tominaga and Dr. Kunitoshi Uchida, National institute for Physiological Sciences (NIPS), found TRPM2 ion channel in pancreatic beta-cells is important for insulin secretion stimulated by glucose and gastrointestinal hormone (incretin) secreted after food intake.  Their finding was reported in Diabetes. Diabetes mellitus is a disease caused by lack of insulin secretion from pancreatic cells, or less response to the secreted insulin, which raises...

2010-10-12 14:03:59

Insulin resistance, a condition in which insulin produced by the body becomes less effective in reducing blood glucose levels, appears to be associated with an increased risk of stroke in individuals without diabetes, according to a report in the October issue of Archives of Neurology, one of the JAMA/Archives journals. Insulin resistance originates from several factors, including genetics, a sedentary lifestyle and obesity, according to background information in the article. The condition...

2010-06-23 13:00:49

Children of mothers whose blood glucose (sugar) was high during pregnancy are more likely to have low insulin sensitivity"”a risk factor for type 2 diabetes"”even after taking into consideration the children's body weight, a new study shows. The results will be presented Tuesday at The Endocrine Society's 92nd Annual Meeting in San Diego. "We know that children born to women with type 2 diabetes or gestational diabetes, or who have high blood sugar during pregnancy are at risk of...

2009-11-12 11:41:55

How a specific gene within the pancreas affects secretion of insulin has been discovered by researchers from the Hebrew University of Jerusalem, in collaboration with Japanese and American universities. Their work opens the way for a new understanding of possible paths to battle diabetes and diabetes-related health problems, which are on the rise all over the world. Blood glucose levels are tightly regulated by secretion of insulin from beta cells in the pancreas. Defective insulin secretion...

2009-09-01 09:48:26

"”A moderate aerobic exercise program, without weight loss, can improve insulin sensitivity in both lean and obese sedentary adolescents, according to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM). Insulin is a hormone produced in the pancreas that permits glucose to enter cells to be used for energy or stored for future use by the body.Because obese adolescents are resistant to insulin, in order to maintain...

2009-05-15 08:57:55

Research from the Johns Hopkins Children's Center reveals that the drug most commonly used in type 2 diabetics who don't need insulin works on a much more basic level than once thought, treating persistently elevated blood sugar "” the hallmark of type 2 diabetes "” by regulating the genes that control its production.Reporting in the May 15 issue of Cell, investigators say they have zeroed in on a specific segment of a protein called CBP made by the genetic switches involved in...

2008-07-31 15:00:24

To: SCIENCE EDITORS Contact: John Ascenzi of Children's Hospital of Philadelphia, +1- 267-426-6050, Ascenzi@email.chop.edu --Could Become First Effective Drug for Rare Genetic Disorder in Children-- PHILADELPHIA, July 31 /PRNewswire-USNewswire/ -- Researchers have used a drug to achieve normal levels of blood sugar in animals genetically engineered to have abnormally high insulin levels. If this approach succeeds in humans, it could become an innovative medicine for children with...


Word of the Day
mallemaroking
  • Nautical, the visiting and carousing of sailors in the Greenland ships.
This word is apparently from a confusion of two similar Dutch words: 'mallemerok,' a foolish woman, and 'mallemok,' a name for some persons among the crew of a whaling vessel.