Latest Hypothalamic-pituitary-adrenal axis Stories

2010-01-12 06:00:00

RESEARCH TRIANGLE PARK, N.C., Jan. 12 /PRNewswire/ -- CeNeRx BioPharma, Inc., a clinical stage company developing and commercializing innovative treatments for diseases of the central nervous system, today reported that a new clinical study shows that its investigational compound CXB722 has potential as a novel anxiolytic, demonstrating a significant effect on both endocrine and cardiovascular biomarkers associated with stress. CXB722 and its prodrug Ayrene (CXB724) are...

2009-05-19 21:02:27

Day-care-center-based child care and insensitive parenting might have lasting effects, U.S. researchers suggest. The Eunice Kennedy Shriver National Institute of Child Health and Human Development tracked about 1,000 children from one month through mid-adolescence to examine the effects of child care in children's first few years of life on later development. The researchers observed children in and out of their homes and when the children were 15, they measured their levels of awakening...

2009-04-21 14:19:54

Study finds link between exposure to community violence and a disruption to the stress pathways in the body School-aged children who witness violence in urban communities show symptoms of post-traumatic stress. They also suffer physiological effects with a disruption to their normal cortisol production pattern during the day, which may have long-term negative effects on their health. According to Dr. Shakira Franco Suglia, from the Harvard School of Public Health, and her team lead by Dr....

2009-01-23 09:43:33

A Canadian/U.S. research team has reported a novel approach to stimulating recovery from chronic stress disorders. Details of the therapeutic model, which exploits the natural dynamics of the body's "fight or flight" system, are published January 23 in the open-access journal PLoS Computational Biology. In contrast to conventional time-invariant therapy, the researchers propose a well-directed therapeutic push delivered according to an optimal treatment schedule.The hypothalamic, pituitary,...

2008-11-18 23:06:38

The relationship between a young child and his or her teacher can affect the levels of the stress hormone cortisol in the child, U.S. researchers believe. Researchers at Washington State University, Auburn University and the Pennsylvania State University said cortisol, a stress hormone in humans, tends to be at its highest levels in the early morning and gradually declines over the course of the day. The researchers found that children in classrooms with about 10 children were more likely to...

2008-08-30 09:00:20

By McNicol, Anne Marie * Context.-In surgical pathology practice adrenal cortical tumors are rare. However, in autopsy series adrenal cortical nodules are found frequently. These are now being identified more commonly in life when the abdomen is scanned for other disease. It is important to differentiate between benign and malignant lesions as adrenal cortical carcinoma is an aggressive tumor. Molecular genetic investigations are providing new information on both pathogenesis of adrenal...

2008-06-14 03:00:00

By Toda, Masahiro Makino, Hiroaki; Kobayashi, Hidetoshi; Morimoto, Kanehisa ABSTRACT. The authors collected saliva samples from 15 married couples and 13 women staying with a female companion (N = 43) during an 8-day stay at a spa resort in Nagano, Japan. To examine changes in endocrinological stress markers, the authors evaluated participants' levels of salivary cortisol and chromogranin A (CgA) by enzyme-linked immunosorbent assay. By the eighth day, women staying with their husbands had...

Word of the Day
  • A murmuring sound; a rushing or whistling sound, like that of the wind; a deep sigh.
  • A gentle breeze; a waft; a breath.
  • Any rumor that engages general attention.
  • A cant or whining mode of speaking, especially in preaching or praying; the chant or recitative characteristic of the old Presbyterians in Scotland.
  • To make a rushing, whistling, or sighing sound; emit a hollow murmur; murmur or sigh like the wind.
  • To breathe in or as in sleep.
  • To utter in a whining or monotonous tone.
According to the OED, from the 16th century, this word is 'almost exclusively Scots and northern dialect until adopted in general literary use in the 19th.'