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Latest Hypothalamus Stories

2009-08-07 00:12:58

The weight-loss effect of leptin, a hormone produced by fat tissue, has been linked to higher levels of the brain chemical dopamine, U.S. researchers said. The animal studies, published in Cell Metabolism, found neurons with receptors for the hormone leptin exist in many parts of the brain -- not just the area controlling satiety. Martin Myers Jr. of the University of Michigan in Ann Arbor says rat studies suggest that in addition to the area controlling the feeling of fullness after eating,...

2009-08-05 11:32:59

As we all know from experience, people eat not only because they are hungry, but also because the food just simply tastes too good to pass up. Now, a new study in the August 6th Cell Metabolism, a Cell Press publication, helps to explain how leptin, a hormone produced by fat tissue, influences that motivation to eat.The researchers describe for the first time a new bunch of leptin-responsive (LepRb) neurons in the brain's lateral hypothalamic area (LHA). Those LHA neurons feed directly into...

2009-07-22 07:14:19

Having trouble losing weight and keeping your type 2 diabetes under control? A key enzyme in the brain may be behind the difficulties. A new study shows decreasing the levels of the brain enzyme prolylcarboxypeptidase (PRCP) led to weight loss and a decreased risk of type 2 diabetes. Researchers studied mice and found  PRCP is located in the hypothalamus. PRCP regulates levels of the alpha-melanocyte stimulating hormone alpha-MSH, which is a peptide known for inhibiting food intake and...

2009-07-21 13:54:30

In a major advance in obesity and diabetes research, Yale School of Medicine scientists have found that reducing levels of a key enzyme in the brain decreased appetites and increased energy levels.Reductions in the levels of the enzyme prolylcarboxypeptidase (PRCP) led to weight loss and a decreased risk of type 2 diabetes in mice, according to research published in the August issue of the Journal of Clinical Investigation. The team found that PRCP is located in the hypothalamus and regulates...

2009-07-21 12:39:36

The peptide alpha-MSH works in a region of the brain known as the hypothalamus to suppress appetite. A team of researchers, at Yale University School of Medicine, New Haven, and the University of California Davis, has provided new insight into the way in which levels of the active form of alpha-MSH are regulated in mice. Specifically, genetic and biochemical analysis performed by the team, led by Sabrina Diano and Craig Warden, indicated that the protein PRCP is expressed in the hypothalamus...

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2009-06-23 16:40:00

 University of California, Berkeley, researchers have found what they think is a critical and, until now, missing piece of the puzzle about how stress causes sexual dysfunction and infertility.Scientists know that stress boosts levels of stress hormones - glucocorticoids such as cortisol - that inhibit the body's main sex hormone, gonadotropin releasing hormone (GnRH), and subsequently suppresses sperm count, ovulation and sexual activity. The new research shows that stress also...

2009-06-02 14:32:22

 In investigating the complex neurocircuitry behind weight gain and glucose control, scientists have known that the hormone leptin plays a key role in the process. But within the myriad twists and turns of the brain's intricate landscape, the exact pathways that the hormone travels to exert its influence have remained a mystery.Now, a study led by investigators at Beth Israel Deaconess Medical Center (BIDMC) sheds further light on the subject. Reported in tomorrow's issue of the journal...

2009-06-02 14:26:54

Mice lacking the fat hormone leptin or the ability to respond to it become morbidly obese and severely diabetic"”not to mention downright sluggish. Now, a new study in the June Cell Metabolism shows that blood sugar control in those animals can be completely restored by returning leptin sensitivity to a single class of neurons in the brain, which account for only a small fraction of those that normally carry the hormone receptors."Just the receptors in this little group of neurons are...

2009-01-23 09:43:33

A Canadian/U.S. research team has reported a novel approach to stimulating recovery from chronic stress disorders. Details of the therapeutic model, which exploits the natural dynamics of the body's "fight or flight" system, are published January 23 in the open-access journal PLoS Computational Biology. In contrast to conventional time-invariant therapy, the researchers propose a well-directed therapeutic push delivered according to an optimal treatment schedule.The hypothalamic, pituitary,...

2009-01-09 00:02:17

Women's brains recognize and encode the smell of male sexual sweat, U.S. psychologists said. Denise Chen of Rice University looked at how the brains of female volunteers processed and encoded the smell of sexual sweat from men. Scientists have long known that animals use scent to communicate, but Chen's findings represent an effort to expand knowledge of how humans' sense of smell complement their more powerful senses of sight and hearing. The researchers studied natural human sexual sweat...


Latest Hypothalamus Reference Libraries

Hypothalamus
2013-03-04 13:43:30

The hypothalamus is an organ that serves as an important link, along the hypothalamic-hypophyseal axis, between the nervous system and the endocrine system. It is located within the cranial cavity, in the cerebrum, right below the thalamus. It also forms the floor of the third ventricle in the brain. It contains neural pathways, blood vessels, glial cells, and secretory cells—all of which work together to control things like body temperature, hunger, thirst, sleep, and hormonal and...

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