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Latest Hypothalamus Stories

2009-06-02 14:32:22

 In investigating the complex neurocircuitry behind weight gain and glucose control, scientists have known that the hormone leptin plays a key role in the process. But within the myriad twists and turns of the brain's intricate landscape, the exact pathways that the hormone travels to exert its influence have remained a mystery.Now, a study led by investigators at Beth Israel Deaconess Medical Center (BIDMC) sheds further light on the subject. Reported in tomorrow's issue of the journal...

2009-06-02 14:26:54

Mice lacking the fat hormone leptin or the ability to respond to it become morbidly obese and severely diabetic"”not to mention downright sluggish. Now, a new study in the June Cell Metabolism shows that blood sugar control in those animals can be completely restored by returning leptin sensitivity to a single class of neurons in the brain, which account for only a small fraction of those that normally carry the hormone receptors."Just the receptors in this little group of neurons are...

2009-01-23 09:43:33

A Canadian/U.S. research team has reported a novel approach to stimulating recovery from chronic stress disorders. Details of the therapeutic model, which exploits the natural dynamics of the body's "fight or flight" system, are published January 23 in the open-access journal PLoS Computational Biology. In contrast to conventional time-invariant therapy, the researchers propose a well-directed therapeutic push delivered according to an optimal treatment schedule.The hypothalamic, pituitary,...

2009-01-09 00:02:17

Women's brains recognize and encode the smell of male sexual sweat, U.S. psychologists said. Denise Chen of Rice University looked at how the brains of female volunteers processed and encoded the smell of sexual sweat from men. Scientists have long known that animals use scent to communicate, but Chen's findings represent an effort to expand knowledge of how humans' sense of smell complement their more powerful senses of sight and hearing. The researchers studied natural human sexual sweat...

2009-01-08 10:27:14

HOUSTON -- A new Rice University study published in the Journal of Neuroscience found that socioemotional meanings, including sexual ones, are conveyed in human sweat. Denise Chen, assistant professor of psychology at Rice, looked at how the brains of female volunteers processed and encoded the smell of sexual sweat from men. The results of the experiment indicated the brain recognizes chemosensory communication, including human sexual sweat. Scientists have long known that animals use scent...

2009-01-07 09:19:09

The first known leptin-sensitizing agents induce mice to lose weightThe discovery more than a decade ago of leptin, an appetite-suppressing hormone secreted by fat tissue, generated headlines and great hopes for an effective treatment for obesity. But hopes dimmed when it was found that obese people are unresponsive to leptin due to development of leptin resistance in the brain. Now, researchers at Children's Hospital Boston report the first agents demonstrated to sensitize the brain to...

2009-01-07 09:02:21

A new study in the January 7th issue of Cell Metabolism, a Cell Press publication, helps to explain why obese people and animals fail to respond to leptin, a hormone produced by fat that signals the brain to stop eating. What's more, they show that two FDA-approved drugs might restore leptin sensitivity, offering a novel treatment for obesity." Most importantly, our study is the first success in sensitizing obese mice on a high-fat diet to leptin," said Umut Ozcan of Harvard Medical School....

2008-12-12 10:29:44

A team of scientists from the University of Cambridge and the University of Cukurova in Turkey have taken a major step to understanding how the brain controls the onset of puberty. The research, published in this week's Nature Genetics, identified the hormone Neurokinin B as a critical part of the control system that switches on the master regulator of human puberty. Although Neurokinin B was previously known to be present in the hypothalamus, the part of the brain that controls puberty, its...

2008-11-06 00:00:04

The fact fetal rats develop a propensity for obesity while in the womb of their fat mothers has implications for humans, University of Buffalo researchers say. In addition, the study found metabolic programming occurs in the fetal hypothalamus, the area of the brain responsible for maintaining the body's energy homeostasis -- body weight -- throughout life. Levels of the hormones insulin and leptin also were elevated in fetuses of these obese mother rats -- abnormalities that have been...

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2008-10-03 07:05:00

U.S. researchers have determined that overeating makes the brain go haywire, which could lead to diabetes, heart disease, and many other problems. Eating too much food activates a typically dormant immune system pathway in the brain. This process sends out immune cells to attack and destroy invaders that are not there, according to Dongsheng Cai of the University of Wisconsin-Madison. The findings were published in the journal Cell. The research could help explain why obesity...


Latest Hypothalamus Reference Libraries

Hypothalamus
2013-03-04 13:43:30

The hypothalamus is an organ that serves as an important link, along the hypothalamic-hypophyseal axis, between the nervous system and the endocrine system. It is located within the cranial cavity, in the cerebrum, right below the thalamus. It also forms the floor of the third ventricle in the brain. It contains neural pathways, blood vessels, glial cells, and secretory cells—all of which work together to control things like body temperature, hunger, thirst, sleep, and hormonal and...

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