Latest Hypothalamus Stories

2009-01-07 09:02:21

A new study in the January 7th issue of Cell Metabolism, a Cell Press publication, helps to explain why obese people and animals fail to respond to leptin, a hormone produced by fat that signals the brain to stop eating. What's more, they show that two FDA-approved drugs might restore leptin sensitivity, offering a novel treatment for obesity." Most importantly, our study is the first success in sensitizing obese mice on a high-fat diet to leptin," said Umut Ozcan of Harvard Medical School....

2008-12-12 10:29:44

A team of scientists from the University of Cambridge and the University of Cukurova in Turkey have taken a major step to understanding how the brain controls the onset of puberty. The research, published in this week's Nature Genetics, identified the hormone Neurokinin B as a critical part of the control system that switches on the master regulator of human puberty. Although Neurokinin B was previously known to be present in the hypothalamus, the part of the brain that controls puberty, its...

2008-11-06 00:00:04

The fact fetal rats develop a propensity for obesity while in the womb of their fat mothers has implications for humans, University of Buffalo researchers say. In addition, the study found metabolic programming occurs in the fetal hypothalamus, the area of the brain responsible for maintaining the body's energy homeostasis -- body weight -- throughout life. Levels of the hormones insulin and leptin also were elevated in fetuses of these obese mother rats -- abnormalities that have been...

2008-10-03 07:05:00

U.S. researchers have determined that overeating makes the brain go haywire, which could lead to diabetes, heart disease, and many other problems. Eating too much food activates a typically dormant immune system pathway in the brain. This process sends out immune cells to attack and destroy invaders that are not there, according to Dongsheng Cai of the University of Wisconsin-Madison. The findings were published in the journal Cell. The research could help explain why obesity...

2008-05-22 14:50:00

Findings could help travelers, shift workers adjust to changes in time zones and overnight schedulesIn investigating the intricacies of the body's biological rhythms, scientists at Beth Israel Deaconess Medical Center (BIDMC) have discovered the existence of a "food-related clock" which can supersede the "light-based" master clock that serves as the body's primary timekeeper.The findings, which appear in the May 23 issue of the journal Science, help explain how animals adapt their circadian...

2008-05-07 09:25:00

New findings of a U.S.-based study showed that blocking a single brain enzyme caused mice to eat less and maintain better blood glucose levels. Researchers hope the results will lead to new improvements in the treatment of obesity and diabetes in humans."We believe we have identified an important drug development target that could potentially turn into a metabolic triple play: appetite control, weight loss and blood sugar management," said Tony Means of Duke University Medical Center in...

2008-05-06 13:50:00

A gut hormone that causes people to eat more does so by making food appear more desirable, suggests a new report in the May issue of Cell Metabolism, a publication of Cell Press. In a brain imaging study of individuals, the researchers found that reward centers respond more strongly to pictures of food in subjects who had received an infusion of the hormone known as ghrelin.The findings suggest that the two drives for feeding"”metabolic signals and pleasure signals"”are actually...

2008-04-07 10:08:31

Why do rats live faster and die younger than humans? A newly discovered biological clock provides tantalizing cluesThis clock, or biological rhythm, controls many metabolic functions and is based on the circadian rhythm, which is a roughly 24-hour cycle that is important in determining sleeping and feeding patterns, cell regeneration, and other biological processes in mammals.The newly discovered rhythm, like the circadian rhythm, originates in the hypothalamus, a region of the brain that...

2007-01-29 16:05:59

ANN ARBOR, Mich. "” A single protein in brain cells may act as a linchpin in the body's weight-regulating system, playing a key role in the flurry of signals that govern fat storage, sugar use, energy balance and weight, University of Michigan Medical School researchers report. And although it's far too early to say how this protein could be useful in new strategies to fight the world's epidemic of obesity, the finding gives scientists an important system to target in future research...

2005-11-03 14:13:48

BOSTON -- A study led by a scientific team at Beth Israel Deaconess Medical Center (BIDMC) provides another important step in our understanding of the critical role that the brain's molecular pathways play in the development of obesity and related disorders. The findings, reported in the November 4, 2005 issue of the journal Cell, demonstrate for the first time that the neuronal pathways that help to keep body weight stable diverge at the melanocortin-4 receptor (MC4R) to regulate either...

Latest Hypothalamus Reference Libraries

2013-03-04 13:43:30

The hypothalamus is an organ that serves as an important link, along the hypothalamic-hypophyseal axis, between the nervous system and the endocrine system. It is located within the cranial cavity, in the cerebrum, right below the thalamus. It also forms the floor of the third ventricle in the brain. It contains neural pathways, blood vessels, glial cells, and secretory cells—all of which work together to control things like body temperature, hunger, thirst, sleep, and hormonal and...

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Word of the Day
  • The offense of persistently instigating lawsuits, typically groundless ones.
  • An unlawful breach of duty on the part of a ship's master or crew resulting in injury to the ship's owner.
  • Sale or purchase of positions in church or state.
This word ultimately comes from the Old French word 'barater,' to cheat.