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Latest Idiopathic CD4+ lymphocytopenia Stories

2012-03-27 01:01:41

The hallmark loss of helper CD4+ T cells during human immunodeficiency virus (HIV) infection may be a red herring for therapeutics, according to a study published on March 26th in the Journal of Experimental Medicine. HIV preferentially infects CD4+ T cells, immune cells required to generate protective antibodies. In many people, this leads to a progressive drop in CD4+ T cell numbers–and the more the numbers fall, the faster AIDS develops. HIV-induced cell loss includes both 'naive'...

2012-03-21 10:24:37

Using data from the Collaboration of Observational HIV Epidemiological Research in Europe (COHERE), Jim Young and colleagues from The Opportunistic Infections Project Team of COHERE show in this week's PLoS Medicine that in successfully treated patients, the risk of a new AIDS event or death follows a CD4 cell count gradient in patients with viral suppression. An increase in CD4 cell count provides the greatest benefit for patients with a CD4 cell count below 200 cells/µL but still...

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2009-04-16 06:05:00

A new report from the Naval Medical Center in San Diego said that CD4+ cell counts among newly-diagnosed HIV patients in the U.S. fell from 1985 to 2007, suggesting the virus may be growing more virulent. CD4+ cells are immune-system cells that are indicate the severity of HIV infection.  As the infection advances, CD4+ cell counts decline. The findings support previous research indicating that patients beginning HIV treatment in recent years may have lower CD4+ cell counts at diagnosis,...

2005-07-14 15:40:00

HIV infection decreases the number of CD4+ T lymphocytes and this increases the risk of infection. Administration of IL-2 to HIV-infected people can boost CD4 cell number, but the mechanisms underlying this were not clear. In a study appearing online on July 14 in advance of print publication of the August 1 issue of the Journal of Clinical Investigation, Joseph Kovacs and colleagues from the NIH use cutting-edge in vivo labeling techniques to show that intermittent administration of IL-2 to...


Word of the Day
reremouse
  • A bat.
The word 'reremouse' comes from Middle English reremous, from Old English hrēremūs, hrērmūs ("bat"), equivalent to rear (“to move, shake, stir”) +‎ mouse.
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