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Purple Sea Urchin Metamorphosis Controlled By Histamine
2012-04-27 07:06:53

Now that hay fever season has started, sufferers are well aware of the effect of histamines. However it is easy to forget that histamine is also a neurotransmitter involved in controlling memories, regulating sleep, and controlling secretion of gastric acid. New research published in BioMed Central's open access journal BMC Developmental Biology shows that for the purple sea urchin (Strongylocentrotus purpuratus) histamine is also responsible for controlling metamorphosis from a free swimming...

2012-04-11 10:39:49

Although observational studies have suggested that losartan, a drug used primarily for the treatment of hypertension, may be associated with an increased risk of death among patients with heart failure compared with other medications in the same class of drugs (angiotensin II receptor blockers [ARBs]), an analysis that included nearly 6,500 patients found that overall, use of losartan was not associated with increased all-cause death or cardiovascular death compared with use of the ARB...

2011-12-19 15:04:26

Chronic obstructive pulmonary disease (COPD) is among the most common causes of death in the US. It is a smoking-related disease for which there are currently no disease-altering therapies. However, hope that one could be developed is now provided by the work of Enid Neptune and colleagues, at Johns Hopkins University, Baltimore, in a mouse model of lung disease caused by exposure to cigarette smoke. Neptune and colleagues found that lostartan, a drug used widely in the clinic (e.g., to...

2011-09-30 05:40:19

(Ivanhoe Newswire) -- A new study suggests adding zoledronic acid to a drug regimen for patients with early stage breast cancer does not improve outcome. Zoledronic acid is a bisphosphonate that is used to treat osteoporosis and prevent skeletal fractures in patients with some types of cancer. In previous studies, bisphosphonates were shown to prevent or delay cancer metastasis and even reduce rates of recurrence and death. Researchers randomly assigned 3,360 patients to receive...

2011-09-26 15:17:32

A drug used to protect bone may extend survival in older breast cancer patients, according to researchers at the Universities of Sheffield and Leeds. The AZURE trial, led by Professor Robert Coleman from the University of Sheffield, has revealed that the bisphosphonate drug zoledronic acid boosts disease-free survival in postmenopausal breast cancer patients but may have an adverse effect on younger women. The full results of the trial were presented today (25 September 2011) at the...

2011-06-17 13:08:00

JERSEY CITY, N.J., June 17, 2011 /PRNewswire/ -- Aoxing Pharmaceutical (NYSE Amex: AXN) ("Aoxing Pharma"), a specialty pharmaceutical company focusing on research, development, manufacturing and distribution of narcotic and pain-management products, announced that its operating subsidiary in China, Hebei Aoxing Pharmaceutical Group Company, has been granted a patent by the State Intellectual Property Office of The People's Republic of China for midazolam maleate oral film. The Chinese...

2011-06-06 20:02:00

A lower dose of zoledronic acid than currently recommended for prevention of bone fractures due to osteoporosis decreases bone resorption and increases bone density, and may be effective in reducing the risk of osteoporotic fractures, a study finds. The new research findings will be presented Monday at The Endocrine Society's 93rd Annual Meeting in Boston. "Our research suggests that one fifth or one half of the recommended dose might be sufficient to decrease fracture risk," said Andrew...

2011-05-23 09:00:00

DEERFIELD, Ill., May 23, 2011 /PRNewswire/ -- Takeda Global Research & Development Center, Inc. U.S., (TGRD U.S.) today announced results from three phase 3 studies of the investigational fixed-dose combination of azilsartan medoxomil plus chlorthalidone (CLD). In two phase 3 studies, azilsartan medoxomil combined in a fixed-dose with CLD lowered clinic systolic blood pressure (SBP) significantly more than the fixed-dose combination of olmesartan medoxomil plus hydrochlorothiazide...

2011-05-23 07:00:00

PARSIPPANY, N.J., May 23, 2011 /PRNewswire/ -- Data evaluating the long-term efficacy and safety of olmesartan medoxomil, amlodipine besylate, plus hydrochlorothiazide (OM/AML + HCTZ) in patients with hypertension aged <65 years and greater than or equal to 65 years, showed that the triple therapy at Week 52 was both well-tolerated and effective in maintaining the blood pressure reductions seen in the pivotal study regardless of age.(1) The pre-specified subgroup analysis results,...


Word of the Day
cenobite
  • One of a religious order living in a convent or in community; a monk: opposed to anchoret or hermit (one who lives in solitude).
  • A social bee.
This word comes from the Latin 'coenobium,' convent, which comes from the Greek 'koinobios,' living in community.
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