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Latest Immune privilege Stories

2013-08-19 13:10:09

In animal studies, CHOP researchers advance new approach to anti-tumor immunotherapy By carefully adjusting the function of crucial immune cells, scientists may have developed a completely new type of cancer immunotherapy—harnessing the body's immune system to attack tumors. To accomplish this, they had to thread a needle in immune function, shrinking tumors without triggering unwanted autoimmune responses. The new research, performed in animals, is not ready for clinical use in...

2013-04-29 15:34:05

The tiny thymus teaches the immune system to ignore the teeming, foreign bacteria in the gut that helps you digest and absorb food, researchers say. When immune cells recognize essential gut bacteria as foreign, inflammatory bowel disease such as ulcerative colitis and Crohn's disease can be the painful, debilitating result. In a study published in the journal Nature, researchers show that the regulatory T cells, or Tregs, that keep this from happening in most of us come from the tiny...

2012-11-30 16:06:17

Molecule called IKBNS in charge of regulatory immune cell maturation Now, scientists at the Helmholtz Centre for Infection Research (HZI) have looked into the origin of Tregs and uncovered a central role played by the protein IkBNS. Armed with this knowledge, the researchers hope to manipulate Tregs in order to either inhibit or activate the immune system. Biochemist Prof. Ingo Schmitz and his team have now published their findings in the scientific journal Immunity. The immune system...

2011-09-19 22:24:18

Within the immune system, a subtle balance exists between the cells that destroy alien pathogens and those that preserve the body's own tissues. When the balance gets out of whack, the cells that normally target viruses or bacteria can go astray, attacking innocent cells and causing autoimmune and inflammatory disease. Now, researchers at the University of North Carolina at Chapel Hill have revealed the genetic underpinnings of the cells —called Foxp3-expressing regulatory T cells or...

2011-09-08 09:43:27

Like humans, mice that live in their natural habitat encounter bacteria and other pathogens that exercise their immune system, yet the lab mice typically used in immunology studies are raised in isolation from most diseases. A study on natural killer cells in wild mice published this week in Molecular Ecology examines the hypothesis that the unsterile living conditions faced by humans and wild mice may improve the readiness of the immune system to fight new infections. The findings suggest...

2010-12-21 07:23:17

(Ivanhoe Newswire) -- For the first time ever it is shown that human fetal immune system arises from a completely different source than the adult immune system, and is more likely to tolerate than fight foreign substances in its environment. This finding could lead to a better understanding of how newborns respond to infections and vaccines, and may explain some mysteries as to why many infants of HIV-positive mothers are not infected with the disease before birth. In addition, it could help...

2010-12-17 16:11:55

UCSF researchers have shown for the first time that the human fetal immune system arises from an entirely different source than the adult immune system, and is more likely to tolerate than fight foreign substances in its environment. The finding could lead to a better understanding of how newborns respond to both infections and vaccines, and may explain such conundrums as why many infants of HIV-positive mothers are not infected with the disease before birth, the researchers said. It also...

2009-05-26 08:49:46

If we imagine our immune system to be a police force for our bodies, then previous work has suggested that the Lymph nodes would be the best candidate structures within the body to act as police stations "“ the regions in which the immune response is organized. However, Prof. Burkhard Becher, University of Zurich, suggests in a new paper "“ published in this week's issue of PLoS Biology "“ that lymph nodes are not essential in the mouse in marshalling T-cells (a main immune...

2009-03-16 10:21:26

One of the most important tasks of the immune system is to identify what is foreign and what is self. If this distinction fails, then the body's own structures will be attacked, the result of which could be an autoimmune disease such as diabetes mellitus type 1 or multiple sclerosis. The only way to protect against these afflictions is to destroy all immune factors that turn against the body's own tissue "“ in other words: immune tolerance. A team working with LMU researcher Dr. David...

2009-02-26 08:48:00

Findings have implications for treating returning vets and others exposed to laser burns BOSTON, Feb. 26 /PRNewswire-USNewswire/ -- Scientists at Schepens Eye Research Institute have shown for the first time that a laser burn to one retina can cause both eyes to lose a special protective ability known as immune privilege. Immune privilege protects the eye without the inflammation of the body's normal immune response, which can further damage delicate eye tissue. This finding, published in...


Word of the Day
monteith
  • A large punch-bowl of the eighteenth century, usually of silver and with a movable rim, and decorated with flutings and a scalloped edge. It was also used for cooling and carrying wine-glasses.
  • A kind of cotton handkerchief having white spots on a colored ground, the spots being produced by a chemical which discharges the color.
This word is possibly named after Monteith (Monteigh), 'an eccentric 17th-century Scotsman who wore a cloak scalloped at the hem.'
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